Olfactory identification performance and olfactory thresholds in patients with schizophrenia were investigated in this study. Three primary questions were raised: (a) Do neuroleptically medicated schizophrenic patients demonstrate significant olfactory identification deficits in the absence of olfactory acuity (threshold) deficits when compared with (i) non-schizophrenic, neuroleptically unrned...

The diagnosis and nosology of Psychotic disorders have been matters of interest and debate since Kraeplin 's original delineation of Manic depressive illness and schizophrenia. Although in the past, it was largely of academic interset, the accurate classification of these disorders has assumed greater importance with the availability of newer and more specific treatments for the psychoses. Abou...

The purpose of this article is to evaluate the role of community and interpersonal functioning in the developmental course and outcome of schizophrenic disorders. Based on a review of the research literature, it appears that certain patterns of poor functioning may be characteristic of at least a subgroup of schizophrenic individuals, predate the onset of the disorder, and predict the outcome o...

The physical and psychological characteristics of hypotonic schizophrenic children are described. It is hypothesized that hypotonic schizophrenia constitutes a homogeneous subgroup within the schizophrenic spectrum. The criteria for diagnosing hypotonic schizophrenia are stated. By selecting a homogeneous subgroup of schizophrenic patients, investigators may improve the probability of identifyi...

Neologism and private usage of stock words have long been considered as uncommon disorders of schizophrenic thought and speech.however,,a review of current literature and psychiatric textbooks reveals few clinical examples.in this article a paranoid  schizophrenic patient with extensive speech disorder has been presented and his neologistic production,private meaning of stoch words and other sp...

The apolipoprotein E (APOE) epsilon4 allele is a known risk factor for the development of Alzheimer's disease, however, an association of the APOE genotype with schizophrenia is controversial. We investigated the association in 60 Korean schizophrenic patients and 60 healthy controls. APOE genotypes were identified by reverse hybridization-based line probe assay. There were significant differen...

OBJECTIVE Research of electroencephalograph (EEG) power spectrum and mean frequency has shown inconsistent results in patients with schizophrenic, schizoaffective and bipolar disorders during medication when compared to normal subjects thus; the characterization of these parameters is an important task. METHODS We applied quantitative EEG (qEEG) to investigate 38 control, 15 schizophrenic, 7 ...

BACKGROUND Electron microscopy and biochemical studies indicate that developmental abnormalities in synaptic organization may be present in brains of schizophrenic patients. This study determined whether these synaptic abnormalities are reflected in differential or uniform alterations in the expression of various synaptic protein genes in the left superior temporal gyrus of schizophrenic patien...

OBJECTIVE The prefrontal cortex exhibits prominent functional, biochemical, and anatomic abnormalities in schizophrenic patients. However, smaller than normal volume of the frontal lobe has not been found in previous postmortem studies of schizophrenic subjects, and magnetic resonance imaging (MRI) scans of schizophrenic subjects have not consistently revealed frontal volumetric deficits. The v...