Biometrics is the science of recognizing people based on their physical or behavioral traits such as face, fingerprints, iris, and voice. Among these characteristics, ocular biometrics has gained popularity due to the significant progress made in iris recognition. However, iris recognition is unfavorably influenced by the non-frontal gaze direction of the eye with respect to the acquisition dev...

PURPOSE The objective of this study was to measure the biomechanical response of the human posterior sclera in vitro and to estimate the effects of age and glaucoma. METHODS Scleral specimens from 22 donors with no history of glaucoma and 11 donors with a history of glaucoma were excised 3 mm posterior to the equator and affixed to an inflation chamber. Optic nerve cross-sections were graded ...

OBJECTIVE To investigate a scaffold-enhanced, light-activated bioadhesive technique as a substitute for sutures in ophthalmic surgery. CLINICAL RELEVANCE Suture use in ophthalmic surgery is technically demanding and time consuming and may be associated with serious complications such as inadvertent ocular penetration, which can result in retinal detachment and endophthalmitis. Bioadhesive sur...

OBJECTIVE To determine the effect of glucose administration on the development of sclera in the chick embryo Gallus domesticus. STUDY DESIGN Experimental study. PLACE AND DURATION OF STUDY Anatomy Department, CPSPRegional Centre, Islamabad, from January 2013 to January 2014. METHODOLOGY The study was carried out in two main groups, control Aand experimental B, which were subdivided into t...

PURPOSE Raman spectroscopy is an effective probe of advanced glycation end products (AGEs) in Bruch's membrane. However, because it is the outermost layer of the retina, this extracellular matrix is difficult to analyze in vivo with current technology. The sclera shares many compositional characteristics with Bruch's membrane, but it is much easier to access for in vivo Raman analysis. This stu...

PURPOSE We aimed to characterize alterations in the posterior scleral collagen microstructure before detectable disease onset in a canine model of open-angle glaucoma caused by an ADAMTS10 mutation. METHODS Collagen orientation, anisotropy degree (proportion of preferentially aligned collagen), and relative density were measured at 0.4 mm spatial resolution using synchrotron wide-angle X-ray ...

PURPOSE To investigate the age-related differences in the inhomogeneous, anisotropic, nonlinear biomechanical properties of posterior sclera from old (22.9 +/- 5.3 years) and young (1.5 +/- 0.7 years) rhesus monkeys. METHODS The posterior scleral shell of each eye was mounted on a custom-built pressurization apparatus, then intraocular pressure (IOP) was elevated from 5 to 45 mm Hg while the ...