background : in this study, we investigated the lethal potency, electrophoretic protein pattern and in vivo effects of hottentotta saulcyi scorpion venom in mice. methods : scorpions were collected at night, by using a uv lamp from mardin province, turkey. venom was obtained from mature h. saulcyi scorpions by electrical stimulation of the telson. the lethality of the venom was determined by i....

Purified scorpion toxin (Leiurus quinquestriatus) slows inactivation of sodium channels in frog muscle at concentrations in the range of 17-170 nM. Mono[125I]iodo scorpion toxin binds to a single class of sites in frog sartorius muscle with a dissociation constant of 14 nM and a binding capacity of 13 fmol/mg wet weight. Specific binding is inhibited more than 90% by 3 microM sea anemone toxin ...

Scorpion stings are a public health problem in south and southwest Iran. There is little information regarding climatological effects on incidence of scorpion stings in Iran. Therefore, the present systemic survey of scorpion sting data was conducted from the point of view of entomo-meteorological relationships and analyzed statistically for the Dezful area in Khuzestan, southwest of Iran. The ...

An updated checklist of the scorpion fauna of Iran, as well as a brief history of taxonomic research on scorpions of Iran is presented. The checklist is based on records of scorpion species whose presence has been confirmed in Iran through field expeditions, examination of scorpion collections, literature review, and personal communications from researchers. The scorpion fauna consists of 51 sp...

    Background: Scorpionism is a public health problem in some provinces in Iran. The present study aimed to assess the clinical manifestations of scorpion envenomation in Shiraz and determine a clinical severity grading for Iranian scorpion envenomation in order to suggest a treatment guideline for emergency physicians.    Methods: In this analytic retrospective stu...

Scorpion envenomation is an important public health hazard in tropical and sub-tropical regions. Envenomation by scorpions can result in a wide range of clinical effects, including, cardiotoxicity, neurotoxicity and respiratory dysfunction. Out of 1500 scorpion species known to exist, about 30 are of medical importance. Although a variety of different scorpion species exist, majority of them pr...

BACKGROUND To observe the inhibition effects of the Buthus matensii Karsch (BmK) scorpion venom extracts on the growth of human breast cancer MCF-7 cells, and to explore its mechanisms. METHODS Two common tumor cells (SMMC7721, MCF-7) were examined for the one which wasmore sensitivity to scorpion venom by MTT method. Cell cycle was determined by flow cytometry. Immunocytochemistry was applie...