Despite the importance of peroxisomal oxidation in branched-chain lipid (phytol, cholesterol) detoxification, little is known regarding the factors regulating the peroxisomal uptake, targeting, and metabolism of these lipids. Although in vitro data suggest that sterol carrier protein (SCP)-x plays an important role in branched-chain lipid oxidation, the full physiological significance of this p...

The beam orientation optimization (BOO) problem in intensity modulated radiation therapy (IMRT) treatment planning is a nonlinear problem, and existing methods to obtain solutions to the BOO problem are time consuming due to the complex nature of the objective function and size of the solution space. These issues become even more difficult in total marrow irradiation (TMI), where many more beam...

The production of effective drugs has continuously been a challenging process for researchers due to the occurrence resistive diseases. Drugs derived from natural product-based compounds as an active scaffold have gained interest in drug development wide range biological properties. Benzoheterodiazepines, product derivative bicyclic chalcones widely reported with various therapeutic potentials....

Objectives/Hypothesis To evaluate the safety and complications of endoscopic airway surgery using supraglottic jet ventilation with a team-based approach. Study Design Retrospective cohort study. Methods Subjects at two academic institutions diagnosed laryngotracheal stenosis who underwent between January 2008 December 2018 were identified. Patient characteristics (age, gender, race, follow-up ...

We recently characterized a novel heart-specific hormone from salmon (salmon cardiac peptide, sCP). We have now prepared a recombinant plasmid expressing the NH(2)-terminal fragment of pro-sCP (NT-pro-sCP) and used it to set up a specific RIA for the peptide. Because of the sensitivity of the assay and the high circulating levels, NT-pro-sCP can be measured from as little as 2 microl of serum. ...

The relationship between PPI and CPI is one of the hotspots in study macroeconomics. Taking China as an example, paper tests dynamic causality during period 2000:M1-2019:M12. In view structural mutations time series variables, bootstrap rolling-window test applied to restudy causal relationship. As a result, it exists bidirectional transmission mechanism PPI, both positive reverse PPI. addition...

Introduction. Operant conditioning of one’s slow cortical potential (SCP) or sensorimotor rhythm (SMR) can be used to control epilepsy or to manipulate external devices, as applied in BCI (Brain-Computer Interface). A commonly accepted view that both SCP and SMR are reflections of central arousal suggests a functional relationship between SCP and SMR networks. Method. The operant conditioning o...

OBJECTIVE During selective cerebral perfusion (SCP), only the upper body is perfused. However, blood actually returns into the descending aorta through collaterals during SCP. This collateral blood flow (CBF) is thought to be important to protect the visceral organs and spinal cord from ischemia. The left subclavian artery is postulated to be important as a collateral source to the lower body. ...

Sterol carrier protein (SCP) is a highly abundant, ubiquitous, low molecular weight protein that has a rapid turnover and multifunctional roles in lipid metabolism and transport. It is also known as the fatty acid-binding protein. These and other characteristics led to studies on the possible role of SCP in mediation of steroidogenic responses of the adrenal gland to corticotropin. To quantitat...

Human–robot teams represent a challenging work application of artificial intelligence (AI). Building strong emotional bonds with robots is one solution to promoting teamwork in such teams, but does this come at cost the form subgroups? Subgroups—smaller divisions within teams—in all human can undermine teamwork. Despite importance question, it has received little attention. We employed mixed-me...