INTRODUCTION The pathogenesis of seborrheic dermatitis has not been fully elucidated. A number of anascogenic yeasts of Malassezia spp. appear to be involved in the intensity of the symptoms. The purpose of the study is to evaluate the levels of selected inflammatory cytokines, IL-2, IL-4, IFN-γ and TNF-α, in the serum after treatment with itraconazole. MATERIAL/METHODS Sixty-six subjects wer...

INTRODUCTION The clinical characteristics of seborrheic dermatitis (SD), therapeutic strategies employed in current clinical practice and impact on the quality of life in the Spanish population are described. METHODS An epidemiological, multicenter, transversal study in patients older than 16 years with seborrheic dermatitis. We evaluated the intensity of symptoms (scale 0-4), and impact on t...

nekam's disease is a rare dermatosis characterized by a distinctive seborrheic dermatitis with prominent facial eruption.  it is further associated with violaceous, papular, and/or nodular lesions on the extremities and trunk, typically arranged in a linear and reticulate pattern.  herein, describe a patient with nekam's disease, which resembled darier’s disease in clinical manifestation.  the ...

disorder characterized by hyperkeratosis, acanthosis, accentuated rete ridges, focal spongiosis, and parakeratosis. It is usually caused by increased sebaceous gland activity, and manifests itself through the apparition of ill-defined eryhematous patches accompanied by fine scaling in areas of high sebum secretion, including the scalp, face, eyebrows, nasal alar creases, melolabial folds, ears,...

BACKGROUND Seborrheic dermatitis is a common chronic disease. Malassezia yeasts have been implicated in the pathogenesis of this disease. Antifungal agents are known to be effective in the treatment of Malassezia yeast infections. OBJECTIVES To evaluate the efficacy of itraconazole in the treatment of mild to severe facial seborrheic dermatitis. METHODS Sixty patients with moderate to sever...

INTRODUCTION The etiology of seborrheic dermatitis is not fully understood. It has been observed that a number of anascogenic yeasts of Malassezia spp. is related to the intensity of the symptoms. The aim of the study is to measure the concentration of selected inflammatory factors IL-2, IL-4, IFN-γ and TNF-α in the serum by an immunoenzymatic method, as well as to confirm the relationship betw...

The aim of our study was to evaluate the role of CD20 and CD45.Ro antibodies in acne and seborrheic dermatitis. A number of 20 patients with papular, pustular or nodular acne and another 20 patients with seborrheic dermatitis were available for our study. We removed bioptic material from all of them and we perform histochemical and immunohistochemical processing within the Laboratory of Histolo...

Pimecrolimus cream 1% has shown to be effective in patients with a variety of inflammatory cutaneous disorders. And it might be a useful modality in the treatment of seborrheic dermatitis. This prospective study was aimed at assessing the efficacy and tolerability of pimecrolimus cream 1% in the treatment of facial seborrheic dermatitis. Twenty patients were instructed to apply pimecrolimus cre...

BACKGROUND Scalp seborrheic dermatitis is a chronic type of inflammatory dermatosis that is associated with sebum secretion and proliferation of Malassezia species. Ketoconazole or zinc-pyrithione shampoos are common treatments for scalp seborrheic dermatitis. However, shampoos comprising different compounds are required to provide patients with a wider range of treatment options. OBJECTIVE T...

BACKGROUND Topical over-the-counter remedies exist to aid in the control of seborrheic dermatitis and chronic dandruff on a superficial level. Low-dose systemic oral nickel and bromide therapy has shown promise in providing improvement and eventual clearing of the disease. OBJECTIVE The purpose of this study was to further evaluate the effect of an orally administered low-dose, homeopathic mi...