It was shown previously (1) that the peak of antibody production in the spleen during the primary response to bovine gamma globulin (BGG) coincides with immature plasma cell proliferation at the border of red and white pulp. The so called "secondary nodules" in the white pulp reach their peak of development after the production of antibodies has subsided. Since the foUieular centers are therefo...

Knowledge of anatomical features of the occlusal surface of cheek teeth (CT) and subocclusal endodontic features (including whether pulp has been properly replaced by secondary dentine) is important in equine dentistry because this may help the clinician determine if the vital, innervated structures of the dentino-pulpal complex have been or might become compromised (e.g., following dental frac...

Due to its predominantly nociceptive innervation, viral tracing from the tooth pulp provides a potential means for tracing central pain pathways. The neural pathways from the tooth pulp to cortex were determined using in situ hybridization to detect the anterograde transneuronal spread of herpes simplex virus type 1 strain H129 following inoculation into the murine mandibular incisor pulp. Viru...

ETHNOPHARMACOLOGICAL RELEVANCE Banana is a fruit with nutritional properties and also with acclaimed therapeutic uses, cultivated widely throughout the tropics as source of food and income for people. Banana peel is known by its local and traditional use to promote wound healing mainly from burns and to help overcome or prevent a substantial number of illnesses, as depression. AIM OF THE STUD...

BACKGROUND Candida has been associated with cases of secondary and persistent root canal infections. The purpose of this study was to evaluate and compare the effectiveness of commonly used intracanal medicament against Candida biofilms found in root canals of human primary teeth with necrotic pulp. MATERIALS AND METHODS Pulp canals of 45 single-rooted primary maxillary anterior teeth with pu...

Pulp exposures secondary to caries are the most common in primary teeth due to the relatively large size of pulp chamber. Pulp in primary teeth is capable of healing, following control of infection and inflammation. Pulpotec and LSTR are the simple noninstrumentation endodontic treatment procedures which are capable of compensating for the inconvenience caused by conventional pulpectomy, and th...

The present study aimed at assesssing – by clinical, histological and radiological investigations – the influence of some external factors on the pulp-dentin complex, and at providing a causal interpretation of the structural changes observed. Materials and methods. Clinical and radiological exams were performed on 65 old patients with ages between 60-75, and also on 40 young patients with ages...

Caries is the most common cause of pulp-periapical disease. When the pulp tissue involved in caries becomes irreversibly inflamed and progresses to necrosis, the treatment option is root canal therapy because the infected or non-infected necrotic pulp tissue in the root canal system is not accessible to the host's innate and adaptive immune defense mechanisms and antimicrobial agents. Therefore...

BACKGROUND Amputation is commonly performed for toe necrosis secondary to peripheral vascular diseases, such as diabetes mellitus. When amputating a necrotic toe, preservation of the bony structure is important for preventing the collapse of adjacent digits into the amputated space. However, in the popular terminal Syme's amputation technique, partial amputation of the distal phalanx could caus...

OBJECTIVES Odontoblasts are highly differentiated post-mitotic cells, which under pathological conditions such as carious lesions and dental injuries may degenerate and be replaced by other pulp cells. We have recently shown that this physiological event can be reproduced in an in vitro assay system, but is highly modified by the presence of unpolymerized resinous monomers. Our hypothesis was t...