Mitochondrial DNA content remains constant between the mature egg and the blastocyst stage in mammals, making this the only period in development when genotypes segregate to daughter cells without the confounding effect of genotype replication. To analyze the segregation patterns of mitochondrial DNA during preimplantation development, we introduced polymorphic mitochondria either peripherally ...

Infection with human immunodeficiency virus (HIV) is associated with neuroimaging alterations. However, little is known about the topological organization of whole-brain networks and the corresponding association with cognition. As such, we examined structural whole-brain white matter connectivity patterns and cognitive performance in 29 HIV+ young adults (mean age = 25.9) with limited or no HI...

Carrier lifetime measurements were performed on deliberately Ti-doped multicrystalline silicon wafers using a temperature controlled photoconductance device. The dominant recombination center was found to be the double-donor level associated with interstitial titanium. The interstitial Ti concentrations in multicrystalline silicon wafers were determined by measuring the Shockley– Read–Hall time...

Modeling and simulation of segregation phenomena in granular flows are investigated. Computational models at different scales ranging from particle level (microscale) to continuum level (macroscale) are employed in order to determine the important microscale physics relevant to macroscale modeling. The capability of a multi-fluid model to capture segregation caused by density difference is demo...

Microsegregation formed during solidification is of great importance to material properties. The conventional Lever rule and Scheil equation are widely used predict solute segregation. However, these models always fail the exact concentration at a high solid fraction because theoretical assumptions. Here, dynamics microsegregation polycrystalline refined Al-Cu alloy studied via two- three-dimen...

In our previous paper, particle and temperature segregations in a fluidized bed of binary particle mixtures were experimentally examined, and heat transfer in the segregated fluidized bed was investigated. As the results, it was shown that the temperature segregation results mainly from low heat transfer coefficient through the interface layer, which exists between the flotsam-rich and jetsam-r...

a comprehensive mathematical model based on the discrete particle model and computational fluid dynamics was utilized to investigate mixing and segregation of particles in fluidized beds at high pressure. to quantify the extent of mixing in the bed, the lacey mixing index was used. simulations were carried out with different mass fractions of small particles at various pressures ranging from 1 ...

We investigate experimentally and theoretically thin layers of colloid particles held adjacent to a solid substrate by gravity. Epifluorescence, confocal, and holographic microscopy, combined with Monte Carlo and hydrodynamic simulations, are applied to infer the height distribution function of particles above the surface, and their diffusion coefficient parallel to it. As the particle area fra...

In this paper, the modeling of solidification Al-4Cu alloy was studied. The calculation code is developed to model equiaxed globular in a square mold. mold walls are subjected constant temperatures and velocity components equal 0, exchange coefficient ’H’ between interface melt estimated at 500 W/( m 2 K) initial temperature ’T0’ 900 K. resolution method used finite differences, upwind scheme f...

We investigate the effect of nanoscale variations in the surface roughness of individual particles on macroscale granular flow characteristics. Experiments were conducted in circular rotating tumblers with smooth and rough 2 and 3 mm steel particles. The smooth beads had a rms surface roughness of approximately 30 to 60 nm; rough beads had a surface roughness of approximately 240 to 350 nm. The...