Targeted cancer therapies have excellent potential for increasing longterm patient survival while minimizing shortand long-term side effects of therapy including neurological problems and secondary cancers. DNA repair systems suppress genome instability that drives the acquisition of tumorigenic mutations. Most cancer therapeutics cause DNA damage, yet despite having DNA repair defects, tumors ...

real-time pricing schemes make the customers to feel the energy price volatility and improve their load profiles. however, these schemes have no significant effect on demand-side uncertainty reduction. in this paper, considering smart grid infrastructures and smart building energy management system (ems), a new real-time pricing scheme is presented to reduce the uncertainty of demand-side. in t...

Our objective is to create subdivision schemes with limit surfaces which are surfaces useful in engineering (spheres, cylinders, cones etc.) without resorting to special cases. The basic idea explored by Sabin et al. [1] in the curve case is that if the property that all vertices lie on an object of the required class can be preserved through the subdivision refinement, it will be preserved int...

Businesses (retailers) often wish to offer personalized advertisements (coupons) to individuals (consumers), but run the risk of strong reactions from consumers who want a customized shopping experience but feel their privacy has been violated. Existing models for privacy such as differential privacy or information theory try to quantify privacy risk but do not capture the subjective experience...

Businesses (retailers) often wish to offer personalized advertisements (coupons) to individuals (consumers), but run the risk of strong reactions from consumers who want a customized shopping experience but feel their privacy has been violated. Existing models for privacy such as differential privacy or information theory try to quantify privacy risk but do not capture the subjective experience...

Drugs that induce human immunodeficiency virus type 1 (HIV-1) replication could be used in combination with highly active antiretroviral therapy (HAART) to reduce the size of the latent reservoir that is in part responsible for viral persistence. Protein kinase C (PKC) is a logical target for such drugs because it activates HIV-1 transcription through multiple mechanisms. Here we show that HIV-...

Masking schemes to secure AES implementations against side-channel attacks is a topic of ongoing research. The most sensitive part of the AES is the nonlinear SubBytes operation, in particular, the inversion in GF(2), the Galois field of 2 elements. In hardware implementations, it is well known that the use of the tower of extensions GF(2) ⇢ GF(2) ⇢ GF(2) ⇢ GF(2) leads to a more efficient inver...

Time or money? That is a question! In this paper, we consider dilemma in the pricing regime, which try to find optimal scheme for identical items with heterogenous time-sensitive buyers. We characterize revenue-optimal solution and propose an efficient algorithm it Bayesian setting. Our results also demonstrate tight ratio between value of wasted time seller's revenue, as well that two common-u...