A study was undertaken to determine the relationship of somatomedin-C as a growth promoting factor to amino acid composition of umbilical venous blood in relationship to fetal growth. In full term pregnancy somatomedin-C from cases with appropriate fetal growth was greater than those with fetal growth retardation. Within the physical parameters of the neonate only birth weight of appropriate fo...

OBJECTIVE Altered serum S100B protein levels have been shown in several psychiatric disorders. Our aim was to investigate whether plasma S100B is different in patients with panic disorder (PD) when compared with controls. Our second aim was to investigate whether treatment with SSRIs have an effect on S100B levels in patients with PD. METHODS The sample included 32 patients diagnosed with PD ...

The pharmacological properties and possible clinical use of trazodon in the treatment of depression are presented. Trazodon is the only antidepressant from the SARI (Serotonin Antagonists and Reuptake Inhibitors) group available in Poland. It has a wide pharmacodynamic profile (being an antagonist of 5-HT2A and 5-HT2C serotoninergic receptors, alpha1 and alpha2 adrenergic receptors as well as H...

BACKGROUND Acute kidney injury (AKI) is often observed in critically ill patients and is associated with high morbidity and mortality. Non-recovery from AKI has a negative impact on the prognosis of affected patients and early risk stratification seems key to improve clinical outcomes. We analyzed metabolites of a conserved key inflammatory pathway (i.e. tryptophan degradation pathway) in seria...

1 The activation of tachykinin NK(1) receptors in the rat spinal cord produced a transient drop in arterial blood pressure followed by a more prolonged pressor effect which is mediated by the stimulation of the sympatho-adrenal system. This study aims at characterizing the spinal mechanism of that initial hypotension occurring in awake unrestrained rats. 2 The initial hypotension (-18+/-2.0 mmH...

Optical spectrum of the sunlight consists of visible or chromatic spectrum, with the range of wavelengths of electromagnetic vibrations from 7700 to 3900 AU, and the invisible spectrum: infrared and ultraviolet. Chromatic spectrum gives rise to the sensation of colour, capable for simulating specialized retinal photoreceptors and is perceptible as light. This rule of perception of the particula...

OBJECTIVES Venlafaxine (VLX), a serotonine-noradrenaline reuptake inhibitor, is one of the most commonly used antidepressant drugs in clinical practice for the treatment of major depressive disorder (MDD). Despite being more potent than its predecessors, similarly to them, the therapeutical effect of VLX is visible only 3-4 weeks after the beginning of treatment. Furthermore, recent papers show...

taxation. We have to create much more awareness of the smoking problem among health professionals than before, and one of the most important messages is the following: smoking cessation treatment is not only a matter of prevention, it is also a part of regular treatment of diseases and rehabilitation.2 At the 6th World Conference on Smoking and Health (November 1987), it was stated that cessati...

The laboratory findings have received some recent modifications. Cerebrospinal fluid (CSF) may be normal or near-normal (protein concentration<100 mg/dL,<15 white blood cells/μL, normal glucose).3 There is a characteristic pattern of radiographic features alongside suggestive clinical manifestations, which lead to a diagnosis of RVCS.This syndrome is characterized:1-clinically by acute-onset an...