objective(s):  oxytetracycline (otc) is a broad spectrum antibiotic widely used for treatment of a wide range of infections. however, its improper human and animal use leads to toxic effects, including hepatonephrotoxicity. our objective was to evaluate protective effects of nigella sativa oil (nso) and/or ascorbic acid (aa), against otc-induced hepatonephrotoxicity in rabbits. materials and me...

Objective(s): Various studies have shown that the diabetes is associated with liver failure. The objective of this study was determining the effects of Berberis vulgaris fruit on histopathological and biochemical markers of liver in diabetic rats. Materials and Methods: In this experimental study, 60 male Wistar rats weighing 200-250 g with free access to water and ad libitum were randomly divi...

Introduction: Experimental evidence suggests positive effects of physical activity on skeletal mass. Biochemical markers determine the response rate of bone metabolism to physical activity. Therefore, the aim of this study was to investigate the effect of Pilates exercise training on serum osteocalcin and parathormone levels in inactive and overweight women. Methods: 28 healthy overweight wome...

The present study was aimed to evaluate the beneficial effect of Cystone syrup in an experimental model of glycerol-induced acute renal failure (ARF) in rats. Biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of Cystone syrup. Administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...

Cardiovascular disease (CVD), especially heart failure (HF) as its common final pathway, is the leading cause of morbidity and mortality worldwide. Furthermore, oxidative and inflammatory processes represent fundamental underlying mechanisms for the development and progression of HF. Of interest, in recent years the development of markers with diagnostic and prognostic value for this pathology ...

BACKGROUND Clinical decision for primary treatment for prostate cancer is dictated by variables with insufficient specificity. Early detection of prostate cancer likely to develop rapid recurrence could support neo-adjuvant therapeutics and adjuvant options prior to frank biochemical recurrence. This study compared markers in serum and urine of patients with rapidly recurrent prostate cancer to...

Precise information on the effects of extracorporeal shockwave therapy (ESWT) biochemical status in humans is still lacking. Hence, this study investigated effectiveness three or six sessions low energy ESWT serum bone metabolism markers individuals who have undergone post anterior cruciate ligament (ACL) reconstruction. Participants with ACL injuries were assigned into groups (n=10 per group),...

Background: Currently, there are no effective markers to diagnose and monitor patients with neuroendocrine tumors (NETs). The aim of this study was assess bone metabolism based on selected turnover: OST, OPG, IGFBP-3, in both the group NETs control group. Associations sociodemographic, biochemical, clinicopathological characteristics were examined. We also evaluated any potential associations b...

the aim of the study was to explore the mechanisms underlying the association of birth weight with later body mass index (bmi) from the biochemical markers related to metabolism and the apa i polymorphism in igf-ii gene.a total of 300 children were selected randomly from the macrosomia birth cohort in wuxi, china. the height and weight were measured and blood samples were collected. plasma conc...

the present study was aimed to evaluate the beneficial effect of cystone syrup in an experimental model of glycerol-induced acute renal failure (arf) in rats. biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of cystone syrup. administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...