background: the early stage of copper poisoning is difficult to be clinically diagnosed in sheep and has not been documented clearly yet. objectives: to assess biomarkers in predicting early copper poisoning in sheep, blood samples were collected from several groups of animals from a naturally copper poisoning occurrence in an industrial region. methods: animals were divided into four experimen...

Although copper has been the subject of numerous researches which have demonstrated that it is essential for normal hemoglobin formation, there have been very few attempts to discover the type of compound in which the element occurs in the case of red blooded animals. Warburg and Krebs (1) approached the problem in experiments on what was referred to as loosely bound copper in blood serum. Usin...

Although copper has been the subject of numerous researches which have demonstrated that it is essential for normal hemoglobin formation, there have been very few attempts to discover the type of compound in which the element occurs in the case of red blooded animals. Warburg and Krebs (1) approached the problem in experiments on what was referred to as loosely bound copper in blood serum. Usin...

Introduction: Copper and zinc play a key role in oxidative reactions and in vivo studies have shown their different effects. In this study we examined the influence of exposure to copper and zinc on catalase and superoxide dismutase (SOD) activities in erythrocytes, total serum antioxidant capacity and malondiadehyde (MDA) production of copper industry workers. Methods: In the present study...

SUMMARY The purpose of this study is to compare the level of zinc, copper and the ratio of zinc to copper in serum of patients who are suffering from acute myocardial infarction with healthy men. In 10 ml blood samples from 45 men on the second day of myocardial infarction and 51 healthy men volunteers matched for age, serum zinc, copper, cholesterol and triglycerides were measured. Zinc and c...

Metal binding strategies employing low molecular weight chelators and equilibrium dialysis were used to investigate several unresolved aspects of zinc and copper binding to serum albumin. Direct measurement of histidine binding to bovine serum albumin when the histidine is presented either as a metal-chelate or alone provides no evidence for an albumin-metal-histidine ternary complex. Using pre...

OBJECTIVE To estimate and compare the levels of serum copper and iron among subjects with oral submucous fibrosis (OSMF) of different clinical stages and healthy controls. STUDY DESIGN Study sample comprised of 50 patients clinically diagnosed with OSMF and 50 healthy controls who were matched for age and gender. OSMF patients were categorised by clinical staging. Serum estimation of copper a...

Copper, a strong prooxidant, may play a role in atherogenesis. The author examined the association between serum copper concentration and mortality from coronary heart disease using data from the Second National Health and Nutrition Examination Survey (1976-1992). Serum copper concentration was determined using atomic absorption spectroscopy. After various exclusions, 151 deaths from coronary h...

BACKGROUND Apart from the crucial role of micronutrients like copper, iron, and zinc in the functions of body enzymes, it seems that changes in the serum levels of these biomarkers may play a role in the pathogenesis of oral cancer. The aim of this study was to measure the serum levels of ferritin, copper, and zinc in patients with oral malignancies. METHODS Sixty consecutive patients with or...

Background: Seborrheic dermatitis is a common chronic relapsing inflammatory skin disease with unknown etiology. Using zinc and selenium supplements have shown some relieving effects on the symptoms of the disease. The present study was conducted to determine the relationship between serum selenium, zinc, and copper levels with seborrheic dermatitis. Methods: A prospective case-control study wa...