BACKGROUND The increasing use of complementary and alternative medicine (CAM) has kindled the need for scientific evaluation of the mechanism of action of CAMs. Although, licorice, a common ingredient in many Traditional Chinese medicine (TCM) has attracted great attention for its antitumor and immunomodulatory activities, the mechanism of action of its polysaccharides is still unclear. Here we...

Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic dermatitis. Myriad pieces of evidence have pointed to the major roles of LL-37 and interleukin-31 (IL31)in atopic dermatitis. The studies on atopic dermatitis are still limited i...

this experiment was performed in order to determine effects of different levels of dietary l-threonine supplementation in male japanese quails’ diets on immune response, small intestinal morphology, blood parameters and microflora.one hundred and forty four, 1-d old japanese quails have been selected and randomly distributed between six treatments and four replicates. basal ration was based on ...

BACKGROUND The current study investigates the anti-stress effects of clove (Eugenia caryophyllus) extracts (0, 200, 400, and 600 mg/kg) on serum antioxidant biomarkers, immune response, immunological organ growth index, and expression levels of acute phase proteins (APPs); ovotransferrin (OVT), ceruloplasmin (CP), ceruloplasmin (AGP), C-reactive protein (CRP), and serum amyloid-A (SAA) mRNA in ...

The ability of 11 laboratory parameters to reflect the degree of activity of Crohn's disease, using a clinical index as reference point was compared by means of multiple stepwise regression analysis. Activity was best defined in decreasing order by orosomucoid, sedimentation rate, C reactive protein, alpha-1-antitrypsin, albumin, haematocrit, IgM, circulating immune complexes, serum iron, IgG, ...

Agrichemicals have been extensively used on crop field to control unwanted invasive weed species. The impact of agrichemicals on aquatic vertebrate species has been a matter of increasing concern to researchers and environmentalist. The present study aimed to evaluate the acute effects of sublethal concentrations (10% of the LC50-96h) of an atrazine based herbicide on several immune system para...

The importance of the reticuloendothelial system in relation to neoplasms has been recently brought into focus by a group of Soviet workers. According to Shimkin (18), blockading of the reticuloendothelial system has been used by Roskin (16) as a means of growing heteroplastic tumors. Bogomolets (3) has reported the effect of specific antireticular cytotoxic serum (ACS) on the genesis, survival...