Sesquiterpene lactones have long been used in traditional Chinese medicines to treat inflammatory diseases. Recently, sesquiterpene lactone family compounds have been recognized as potential anticancer agents. Thus, it is necessary to explore new sesquiterpene lactones and their antitumor mechanism for cancer treatments. In the present study, we have explored the potential anti-cancer activity ...

AROMATICINE (SYSTEMATIC NAME: 4a,8-dimethyl-3-methyl-ene-3,3a,4,4a,7a,8,9,9a-octa-hydro-azuleno[6,5-b]furan-2,5-dione), C(15)H(18)O(3), is a natural lactone isolated from Amblyopappus pusillus. The mol-ecular structure and conformation agree with the results of Romo, Joseph-Nathan & Díaz [(1964 ▶). Tetra-hedron, 20, 79-85]. The fused-ring system contains a seven-membered ring in a twist-boat co...

THE TITLE COMPOUND [SYSTEMATIC NAME: 3,8-dihydr-oxy-3-(hydroxy-meth-yl)-9-methyl-6-methyl-enedeca-hydro-azuleno[4,5-b]furan-2(3H)-one], C(15)H(22)O(5), is a sesquiterpene lactone showing the typical tricyclic guaianolide skeleton which has been isolated, together with other related metabolites, from the plant Centaurea musimomum. The present study confirms the mol-ecular structure, assigned by ...

Parthenin (a sesquiterpene lactone) is a major constituent of parthenium hysterophorus –a noxious weed known for its environmental and health hazardous properties. . It is responsible for imparting the several properties to this weed such as allelpathy, autotoxicity and allergencity. Further, anticancerous, antiameobic and antimalarial properties of the weed are also credited to parthenin. The ...

A population of Parthenium hysterophorus collected in Salta Argentina afforded two ambrosanolides, 2beta-hydroxycoronopilin and 1alpha,2beta,4beta-trihydroxypseudoguaian-6beta,12-olide, as well as five known others. Plants of the fructification from those transplanted from the Puna Argentina at 1200 m over the sea level produced hymenin.