Atherosclerosis is a chronic inflammatory disease of arteries. It is triggered by proinflammatory mediators which induce adhesion molecules (eg, vascular cell adhesion molecule [VCAM]-1) in endothelial cells (ECs) by activating p38 and c-Jun N-terminal kinase (JNK) mitogen-activated protein (MAP) kinases by phosphorylation. Blood flow influences atherosclerosis by exerting shear stress (mechani...

This paper describes the application of refined plate theory to investigate free vibration and buckling analyses of functionally graded nanocomposite plates reinforced by aggregated carbon nanotube (CNT). The refined shear deformation plate theory (RSDT) uses four independent unknowns and accounts for a quadratic variation of the transverse shear strains across the thickness, satisfying the zer...

There are a number of parameters influencing the dynamic and seismic response of bridges. Of these, two important parameters warranting special notice include: the properties of the neoperenes in the state of connection between girders and columns and the shear stiffness of underlying soil in the level of bridge substructure’s connectivity to the ground. In this paper, the effects of these tw...

In the present work, thermo-electro vibration of the piezoelectric nanoplates resting on the elastic foundations using nonlocal elasticity theory are considered. In-plane and transverse displacements of the nanoplate have been approximated by six different modified shear deformation plate theories considering transverse shear deformation effects and rotary inertia. Moreover, two new distributio...

It is known that marine sediments can support both compressional and shear waves. However, published work on scattering from irregular elastic media has not examined the influence of shear on sea bed scattering in detail. A perturbation model previously developed by the authors for joint roughness-volume scattering is used to study the effects of elasticity for three sea bed types: sedimentary ...

There are a number of parameters influencing the dynamic and seismic response of bridges. Of these, two important parameters warranting special notice include: the properties of the neoperenes in the state of connection between girders and columns and the shear stiffness of underlying soil in the level of bridge substructure’s connectivity to the ground. In &#10this paper, the effects of these ...

BACKGROUND Regions in the vasculature exposed to steady laminar flow have a lower likelihood for atherosclerosis than regions exposed to disturbed flow with low shear stress. We previously found that laminar flow of short duration inhibited tumor necrosis factor (TNF)-alpha-mediated proinflammatory signaling in cultured endothelial cells (ECs). However, mechanisms responsible for the atheroprot...

this paper addresses the combined effects of couple stresses, thermal radiation, viscous dissipation and slip condition on a free convective flow of a couple stress fluid induced by a vertical stretching sheet. the cogley- vincenti-gilles equilibrium model is employed to include the effects of thermal radiation in the study. the governing boundary layer equations are transformed into a system o...

In this research, using the Modified Compression Field Theory (MCFT), a new truss based model is proposed to predict the behavior of reinforced concrete coupling beams with diagonal reinforcement. The model is able to consider the effects of shear and axial forces and bending moment, simultaneously. The proposed model includes a nonlinear shear spring, an axial spring, two inclined truss member...

The classical shell theory, first-order shear deformation theory, and third-order shear deformation theory are employed to study the natural frequencies of functionally graded cylindrical shells. The governing equations of motion describing the vibration behavior of functionally graded cylindrical shells are derived by Hamilton’s principle. Resulting equations are solved using the Navier-type s...