PURPOSE To evaluate and compare Comfilcon A and Senofilcon A silicone hydrogel contact lenses used as a therapeutic bandage following transepithelial excimer laser photorefractive keratectomy (PRK). METHODS Patients undergoing transepithelial PRK for myopia were prospectively recruited. Included patients had a Comfilcon A silicone hydrogel lens inserted in one eye, with a Senofilcon A lens in...

Diffusion of tear film components through a hydrogel contact lens is significantly influenced by its interactions with material. In our study Cu and Mn ions were used to describe transport properties of the membranes which were hydrogel contact lens materials. Ion concentrations were measured by an electron spin resonance (ESR) spectrometer, and differential scanning calorimetry (DSC) was used ...

This study compared tear function tests and cytologic changes on the conjunctival surface in asymptomatic patients wearing contact lens of different materials. Included in this study were 40 eyes wearing daily wear 4 week replacement hydrogel (H) lenses, 32 eyes wearing silicone hydrogel (SiH) lenses, 18 eyes wearing rigid gas-permeable (RGP) lenses, and 21 healthy eyes (no lenses) as the contr...

PURPOSE To quantify the end-of-day silicone-hydrogel daily disposable contact lens fit and its influence of on ocular comfort, physiology and lens wettability. METHODS Thirty-nine subjects (22.1±3.5 years) were randomised to wear each of 3 silicone-hydrogel daily-disposable contact lenses (narafilcon A, delefilcon A and filcon II 3), bilaterally, for one week. Lens fit was assessed objectivel...

PURPOSE The purpose of this study was to evaluate ciprofloxacin-releasing silicone hydrogel contact lens materials in vitro and in vivo for the treatment of microbial keratitis. METHODS Model silicone hydrogel contact lens materials were manufactured using a molecular imprinting technique to modify ciprofloxacin release kinetics. Various contact lens properties, including light transmission a...

Significant advances during the past decade in silicone hydrogel lenses have made them the primary mode for new contact lens wear. Their dominance in the market place is driven largely by the elimination of structural and physiological changes induced by contact lens-induced hypoxia, as exemplified especially by the reduction in limbal redness. However, end-of-day dryness and discomfort still d...

PURPOSE This study compared a new contact lens rewetting drop containing both carboxymethylcellulose and hyaluronic acid (CMC-HA) with a standard drop containing carboxymethylcellulose only (CMC). Symptoms of discomfort typical in lens wear and lid wiper epitheliopathy (LWE) were assessed over a 3-month period in a diverse sample of contact lens wearers. METHODS Adapted daily-wear contact len...

in order to increase the water content and the oxygen permeability of hydrogels used in themanufacture of contact lenses, the polar monomer silicon hydrogel contact lenses (shcl), and 2-hydroxyethyl methacrylate (hema) were copolymerized with the hydrogels. due to the presence ofpolar monomers in the conventional contact lenses, the major component of the human tear,lysozyme is extensively adso...