The number of pesticides used in agriculture is increasing steadily, leading to contamination of soil and drinking water. Herein, we present a microfluidic platform to detect the extent of contamination in soil samples. A microchip capillary electrophoresis system with in-channel electrodes was fabricated for label-free electroanalytical detection of triazine herbicides. The sample mixture cont...

Much uncertainty exists regarding the discharge characteristics of terrestrial-use herbicides into aquatic systems. This study evaluated the temporal distribution and concentrations of five commonly used herbicides (atrazine, bromacil, metolachlor, norflurazon, and simazine) in a typical South Florida watershed. Surface water samples were collected weekly over a 3-yr period from four canals and...

Inside the framework of Analytical Quality by Design, a model-based approach has been developed and used to identify operating conditions (control method parameters) related composition flow rate mobile phase for liquid chromatographic determination with preset quality characteristics. The starts defining these desired characteristics intended chromatogram (proper resolution consecutive peaks s...

A.1 Toxicity to Birds / Reptiles ......................................................................................... 2 A.1.1 Birds: Acute Oral Studies .................................................................................... 2 A.1.2 Birds: Subacute Dietary Studies .......................................................................... 4 A.1.3 Birds: Chronic Studies.............

A small hydrological basin (Lerma, NE Spain), transformed from its natural state (steppe) to rain-fed agriculture and recently to irrigation agriculture, has been monitored across four seasons of an agricultural year. The goal of this study was to assess how and whether agricultural activities impacted the nearby freshwater ecosystems via runoff. Specifically, we assessed the toxicity of three ...

BACKGROUND Atrazine is a potent endocrine disruptor that increases aromatase expression in some human cancer cell lines. The mechanism involves the inhibition of phosphodiesterase and subsequent elevation of cAMP. METHODS We compared steroidogenic factor 1 (SF-1) expression in atrazine responsive and non-responsive cell lines and transfected SF-1 into nonresponsive cell lines to assess SF-1's...

To improve understanding of the factors affecting pesticide occurrence in ground water, patterns of detection were examined for selected herbicides, based primarily on results from the National Water-Quality Assessment (NAWQA) program. The NAWQA data were derived from 2,227 sites (wells and springs) sampled in 20 major hydrologic basins across the USA from 1993 to 1995. Results are presented fo...