نتایج جستجو برای: single nucleotide polymorphism snp

تعداد نتایج: 1023032  

Journal: :iranian journal of allergy, asthma and immunology 0
ali mosayebian department of immunology, school of medicine, isfahan university of medical sciences, isfahan, iran. mazdak ganjalikhani-hakemi cellular and molecular immunology research center, faculty of medicine, isfahan university of medical sciences, isfahan, iran. rezvan meshkat department of immunology, faculty of medicine, shahrekord university of medical sciences, shahrekord, iran. ramin ghasemi department of immunology, school of medicine, isfahan university of medical sciences, isfahan, iran. hossain khan-ahmad department of genetics and molecular biology, faculty of medicine, isfahan university of medical sciences, isfahan, iran. morteza samadi department of immunology, faculty of medicine, shahid sadoughi university of medical sciences, yazd, iran and reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, iran.

the snp (rs11209026, arg381gln, r381q) in the il-23 receptor (il23r) confers protection against multiple inflammatory diseases, representing one of the most significant human genetic polymorphisms in inflammatory diseases. we, therefore, investigated the association between il-23 r r381q gene polymorphism and asthma.this case-control study was performed on 209 patients, and 200 healthy controls...

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ژورنال: :iranian red crescent medical journal 0
zahra mojtahedi shiraz institute for cancer research, shiraz university of medical sciences, ir iran nasroolah erfani shiraz institute for cancer research, shiraz university of medical sciences, ir iran mahyar malekzadeh shiraz institute for cancer research, shiraz university of medical sciences, ir iran mohammad reza haghshenas shiraz institute for cancer research, shiraz university of medical sciences, ir iran abbas ghaderi shiraz institute for cancer research, shiraz university of medical sciences, ir iran alamtaj samsami dehaghani department of obstetrics and gynecology, shiraz university of medical sciences, ir iran +98-7112303687, [email protected]; department of obstetrics and gynecology, shiraz university of medical sciences, ir iran +98-7112303687, [email protected]

background the association between her2 ile655val single nucleotide polymorphism and cancer is controversial. objectives the aim of our study was to investigate this polymorphism in patients with ovarian cancer. patients and methods genomic dna was extracted from peripheral blood leukocytes of 107 patients and 130 healthy women. her2 gene polymorphism was assessed by pcr-rflp. results no signif...

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Journal: :The Stata Journal: Promoting communications on statistics and Stata 2005

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Journal: :hepatitis monthly 0
jie fan department of epidemiology, school of public health and management, research center for medicine and social development, innovation center for social risk governance in health, chongqing medical university, chongqing, china xin huang department of epidemiology, school of public health and management, research center for medicine and social development, innovation center for social risk governance in health, chongqing medical university, chongqing, china juan chen key laboratory of molecular biology for infectious diseases, institute for viral hepatitis, department of infectious diseases, the second affiliated hospital, chongqing medical university, chongqing, china yiling cai obstetrics and gynecology department, chengdu women and children’s central hospital, sichuan province, china lin xiong maternal and child health hospital of chongqing yuzhong district, chongqing, china lihong mu department of epidemiology, school of public health and management, research center for medicine and social development, innovation center for social risk governance in health, chongqing medical university, chongqing, china; research center for medicine and social development, innovation center for social risk governance in health, school of public health and management, chongqing medical university, chongqing, china. tel/fax: +86-2368485008

background hepatitis b virus (hbv) infection is a serious public health problem in china and worldwide. mother-to-child transmission is one of hbv’s main transmission routes in highly endemic regions. genome-wide association studies (gwas) identify single nucleotide polymorphisms (snps) at hla loci as associated with hbv infection. however, the mechanisms of hbv perinatal transmission and break...

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Journal: :iranian journal of basic medical sciences 0
tausif ahmed rajput department of biochemistry and molecular biology, centre for research in experimental and applied medicine (cream), army medical college, national university of sciences & technology (nust), islamabad, pakistan abdul khaliq naveed department of biochemistry and molecular biology, centre for research in experimental and applied medicine (cream), army medical college, national university of sciences & technology (nust), islamabad, pakistan shakir khan department of biochemistry and molecular biology, centre for research in experimental and applied medicine (cream), army medical college, national university of sciences & technology (nust), islamabad, pakistan zia-ur rehman farooqi department of biochemistry and molecular biology, centre for research in experimental and applied medicine (cream), army medical college, national university of sciences & technology (nust), islamabad, pakistan

objective(s):organic anion transporter polypeptide 1b1 (oatp1b1) encoded by solute carrier organic transporter 1b1 (slco1b1) gene; a transporter involved in the uptake of drugs and endogenous compounds is present in hepatocyte sinusoidal membrane. aim of this study was to investigate the frequencies of functionally significant snps (388a>g and 521t>c) and their haplotypes in 6 ethnic groups of ...

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ژورنال: :thrita 0
bahareh moradi najafabad branch, islamic azad university, najafabad, isfahan, iran hossein tabatabaeian genetics division, biology department, faculty of sciences, university of isfahan, isfahan, iran samira sadeghi genetics division, biology department, faculty of sciences, university of isfahan, isfahan, iran mansoureh azadeh najafabad branch, islamic azad university, najafabad, isfahan, iran kamran ghaedi cellular and molecular biology division, biology department, faculty of sciences, university of isfahan, isfahan, iran; cellular and molecular biology division, biology department, faculty of sciences, university of isfahan, isfahan, iran. tel: +98-3137932479, fax: +98-3137932456

conclusions rs1595065 could be recommended as a risk factor in regulating her4 expression and affecting her2 positivity incidence among bc patients. methods overall, 156 patients and controls were genotyped using rflp-pcr. armitage test for trend was utilized to investigate the association between rs1595065 and susceptibility to bc. the possible change in the interaction between rs1595065 and m...

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Journal: :iranian journal of applied animal science 2015
b. hemati s. gharaie-fathabad m.h. fazeli z. namvar m. ranji

in the present research, molecular detection of bovine leukocyte adhesion deficiency (blad) and complex vertebral malformation (cvm)in a population of iranian holstein cows has been carried outusing milk somatic cells by polymerase chain reaction-restriction fragment length polymorphism(pcr-rflp). the blad and cvm are monogenic and autosomal recessive heredity lethal syndrome in holstein-friesi...

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ژورنال: :iranian red crescent medical journal 0
xin liu department of epidemiology and biostatistics, school of public health, jilin university, changchun, china shuang li department of epidemiology and biostatistics, school of public health, jilin university, changchun, china xuejun lin department of epidemiology and biostatistics, school of public health, jilin university, changchun, china kangkang yan department of epidemiology and biostatistics, school of public health, jilin university, changchun, china longyu zhao department of epidemiology and biostatistics, school of public health, jilin university, changchun, china qiong yu department of epidemiology and biostatistics, school of public health, jilin university, changchun, china; qiong yu, department of epidemiology and biostatistics, school of public health, jilin university, changchun, china. tel: +86-43185619451, fax: +86-43185619163

objectives the aim of this study was to explore the association between axin2 gene polymorphism and papillary thyroid carcinoma (ptc). patients and methods 106 blood samples (56 ptc patients and 50 healthy controls) were drawn from china-japan :union: hospital in jilin province, china, during october 2010 to march 2011. a case-control study was designed to examine the association between axin2 ...

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Journal: :avicenna journal of medical biochemistry 0
iraj khodadadi department of biochemistry, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran; department of biochemistry, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran. tel: +98-8138380572

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Journal: :health scope 0
hooshang rafighdoost cellular and molecular research center, zahedan university of medical sciences, zahedan, ir iran; department of anatomy, school of medicine, zahedan university of medical sciences, zahedan, ir iran zahra rafighdoost department of anatomy, school of medicine, zahedan university of medical sciences, zahedan, ir iran mohsen taheri genetics of non communicable disease research center, zahedan university of medical science, zahedan, ir iran; corresponding author: mohsen taheri, corresponding author: mohsen taheri, genetics of non communicable disease research center, zahedan university of medical science, zahedan, ir iran, tel: +54-13416703, fax: +54-13416708

results no significant difference was found between the groups regarding bmht rs3797546 gene polymorphism. the c allele was not associated with ns-cl/p (or = 1.27, 95% ci = 0.85-2.79, p = 0.690). conclusions our data suggested that bmht rs3797546 gene polymorphism was not associated with risk/ protection for ns-cl/p in a sample of iranian population. larger studies are required to validate our ...

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