BACKGROUND Sinonasal mucosal melanoma is a rare neoplasm with a poor prognosis. METHODS Retrospective analysis was conducted on 78 patients with localized sinonasal mucosal melanoma treated at Memorial Sloan Kettering Cancer Center (MSKCC from 1998-2013). Demographic, tumor, imaging, and treatment factors were recorded and survival and disease-control outcomes were analyzed. RESULTS Median ...

Objectives. Hemangiopericytoma is a rare tumor entity deriving from pericytes. Less than 5% of hemangiopericytoma occur in the nasal cavity and are characterised by a rather benign nature with low tendency of metastasis. However, as the recurrence rate in the literature ranges from 9.5% to 50%-depending on the length of followup-a radical surgical resection is considered as the gold-standard tr...

BACKGROUND Mucosal melanoma is a rare malignancy arising from melanocytes of the mucosal surfaces. The pattern and frequency of oncogenic mutations and histopathological biomarkers have a role on distinct tumour behaviour and survival. AIMS To assess the rate of C-KIT positivity and its effect on survival of surgically treated sinonasal malignant melanoma patients with other histopathological...

INTRODUCTION Metastatic adenocarcinoma from the gastrointestinal tract to the sinonasal tract is rare. The histological morphology of this lesion is indistinguishable from the colonic variant of primary sinus adenocarcinoma or intestinal-type adenocarcinoma (ITAC). CLINICAL PICTURE This is a report of a case of metastatic adenocarcinoma of colorectal origin to the paranasal sinuses in a 52-ye...

BACKGROUND The purpose of this study was to evaluate the outcome in sinonasal mucosal melanoma (SMM). METHODS A retrospective analysis of clinicopathological data from January 1976 to December 2005 was performed. Survival curve, univariate, and multivariate analyses were undertaken. RESULTS Sixty-eight patients with SMM were enrolled; 3 patients refused treatment. The 3-year and 5-year over...

Hepatocellular carcinoma most often metastasizes to the lungs, abdominal lymph nodes, or bone. The identification of extrahepatic metastases of hepatocellular carcinoma to the sinonasal region has rarely been reported. We report a case of a 49 year-old man with a history of stage IV hepatocellular carcinoma presenting with two adjacent pigmented lesions on the tip of his nose. Initial pathologi...

Carcinomas arising in pre-existing sinonasal papillomas of the nasal septum are rare. To our knowledge only one case has been reported. We report two cases of carcinomas occurring in septal papillomas. In the first case a carcinoma developed in an exophytic papilloma 16 years after the first operation for a papilloma. In the second case a carcinoma was present at the first presentation within a...

Mucosal malignant melanoma of the head and neck is a rare but aggressive type of melanoma with poor clinical prognosis and outcome. Its nonspecific symptomatology frequently leads to its delayed diagnosis until advanced stages of the disease. The author presents a case of primary sinonasal amelanotic melanoma with preoperative F-18 FDG PET/CT showing diffuse bone metastasis only two months afte...

Metastasis to the breast from an extramammary malignant neoplasm, including esthesioneuroblastoma, is uncommon. The present study describes a rare case of sinonasal esthesioneuroblastoma, Hyams' histologic grade 2, Kadish's stage C, T4N0M0, in a 30-year-old female. The patient underwent a radical ethmoidectomy with external beam radiotherapy, followed by chemotherapy including five cycles of ci...