OBJECTIVE The study purpose was to detect the value of magnetic resonance imaging (MRI) compared to computed tomography (CT) and different imaging modalities as conventional radiology in evaluation of sinonasal neoplasms diagnosed by Histopathology. METHODS Thirty patients (16 males and 14 females) were complaining of symptoms related to sinonasal tract. After thorough clinical and local exam...

BACKGROUND The level of p53 protein expression in sinonasal squamous cell carcinoma (SNSCC) has been estimated, but the results remain inconsistent and the point of consensus has not been reached. This study was first determined to evaluate the clinical effects of p53 expression in SCC of the sinonasal tract. METHODS According to the preferred reporting items for systematic reviews and meta-a...

BACKGROUND Adenocarcinoma is a rare tumor of the sinonasal tract. The purpose of this study was to characterize a single institution's experience with this malignancy. METHODS Retrospective review was performed of patients with adenocarcinoma of the sinonasal tract from 1993 to 2009. Demographic data, disease presentation, treatment, and survival rates were collected and evaluated. RESULTS ...

SMARCB1 (INI1)-deficient sinonasal carcinoma is a recently described variant of sinonasal tract carcinoma characterized by complete loss of nuclear SMARCB1 (INI1). It is very rare and currently underdiagnosed because of a lack of awareness. Before the description of SMARCB1 (INI1)-deficient sinonasal carcinomas, these tumors were probably misclassified as various malignant neoplasms. To date, o...

Schwannomas or neurilemmomas are tumors of benign nerve sheath, and between 25 and 45% of all arise in the head and neck region. Less than 4 % are found in the sinonasal tract and their diagnosis may have difficulty due to non-specific symptoms and image characteristics. In several cases, complete surgical removal by endoscopic approach is the treatment of choice in these tumors. We report the ...

Eosinophilic angiocentric fibrosis (EAF) is a rare submucosal fibrosis without a well-developed differential diagnosis. Three cases of sinonasal tract EAF were identified in 2 women and 1 man, aged 49, 64, and 28 years, respectively. The patients experienced a nasal cavity mass, maxillary pain, or nasal obstructive symptoms of long duration. The process involved the nasal septum (n = 2), nasal ...

BACKGROUND The impact of tumor differentiation on the behavior and response of sinonasal neuroendocrine carcinoma is unknown. METHODS We performed a retrospective review of the patients treated for neuroendocrine carcinoma (NEC) of the nasal cavity or paranasal sinuses from 1992 to 2008 at MDACC. RESULTS The results of our study suggest that pathologic differentiation may not be a critical ...