In this paper, we present a novel methodology to solve the problem of delineating homogeneous site-specific management zones (SSMZ) in agricultural fields. This consists dividing field into small regions for which specific rate inputs is required. The objective minimize number zones, must be according soil property: physical or chemical. Furthermore, as opposed oval SSMZ with rectangular shapes...

The Internet increasingly serves as a platform for the delivery of public health interventions. The efficacy of Internet interventions has been demonstrated across a wide range of conditions. Much more work remains, however, to enhance the potential for broad population dissemination of Internet interventions. In this article, we examine the effectiveness of Internet interventions, with particu...

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i List of Figures iii List of Table iv

Site-directed mutagenesis is still a very efficient strategy to elaborate improved enzymes. Recently, advances have been made in developing rational strategies aimed at reshaping enzyme specificities and mechanisms, and at engineering biocatalysts through molecular assembling. These knowledge-based studies greatly benefit from the most recent computational analyses of enzyme structures and func...