In the late stages of muscle development, a unique cell population emerges that is a key player in postnatal muscle growth and muscle regeneration. The location of these cells next to the muscle fibers triggers their designation as satellite cells. During the healing of injured muscle tissue, satellite cells are capable of forming completely new muscle fibers or restoring damaged muscle fibers....

Cell proliferation is an important biological process during myogenesis. Tob1 encoded a member of the Tob/BTG family of anti-proliferative proteins. Our previous LongSAGE (Long Serial Analysis of Gene Expression) analysis suggested that Tob1 was differentially expressed during prenatal skeletal muscle development. In this study, we isolated and characterized the swine Tob1 gene. Subsequently, w...

skeletal deformities are a common problem in fish hatcheries and commercial farms that affect growth, development and survival as well as the market value of the final product. among the nutritional components, phosphorus (p) and calcium (ca) are of special interest as they are directly involved in the development and maintenance of the skeletal system. hence, the present study was carried out ...

objective: micrornas (mirnas) are a class of small non-coding rnas that play pivotal roles in many biological processes such as regulating skeletal muscle development where alterations in mirna expression are reported during myogenesis. in this study, we aimed to investigate the impact of predicted mirnas and their target genes on the myoblast to myocyte differentiation process. materials and m...

We have recently completed investigations into the effects of acute illness and of starvation on the skeletal development of albino rats of the Sprague-Dawley strain (Acheson & Macintyre, 1958a, b ; Acheson, 1959). In planning this work we found it necessary to devise our own methods and techniques for frequent measurement and radiography of rats. The techniques proved to be satisfactory and we...

Multiple hereditary exostosis, EXT genes, and skeletal development.

it has been reported that cither lithium or verapamil can potentiate the neuromuscular blocking activity of certain neuromuscular blockers. in the present investigation, possible interaction of verapamil with lithium has been described. the dose ■ response effects of verapamil and lithium on diaphragmatic contractility were assessed in vitro. mechanical responses of the muscle to indirect (nerv...

introduction: osteoporosis is a multifactorial disease and several factors are involved in development and progression of the disease. the aim of this study was to increase our understanding of the relation between age, weight, bmi, postmenopausal age and bone mineral density in post menopause women. methods: 240 azarbaijani women aged 50-70 years having inclusion criteria were recruited. bone ...