BACKGROUND We investigated how body size and physical activity influence the risk of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). METHODS In the Netherlands Cohort Study (n = 120,852), risk factors were self-reported at baseline in 1986. After 7.3 years of follow-up, 603 cases and 4,631 sub-cohort members were available. CIMP status according to the Weisenberger mark...

A man in his twenties approaches the bar. He wears a brown collared shirt. He has a full head of hair. He looks like a normal guy. The room is bustling. A woman is visible in the corner, nursing a bottle of beer. Is she single? This looks like the perfect place for a guy like this. The young man appears puzzled for a moment. He addresses the bartender, “Can I get a light beer?” The bartender, a...

Abstract Gypseous soils are considered one of the most problematic soils. The skirted foundation is an alternative technology that works to improve bearing capacity and reduce settlement. This paper investigates use square foundations resting on gypseous soil subjected concentric eccentric vertical load with eccentricity values 4, 8, 17 mm in 16 experimental model tests. To obtain results by us...

A key question in the interaction of droplets with lubricated and liquid-infused surfaces is what determines apparent contact angle droplets. Previous work has determined this using measured values geometry `skirt' -- meniscus-like deformation that forms around base deposited droplet. Here, we consider theoretically equilibrium a droplet on smooth, impermeable lubricant-coated surface, argue sm...

We develop T-SKIRT: a temporal, structuredknowledge, IRT-based method for predicting student responses online. By explicitly accounting for student learning and employing a structured, multidimensional representation of student proficiencies, the model outperforms standard IRTbased methods on an online response prediction task when applied to real responses collected from students interacting w...