Background Various pathophysiological mechanisms such as microvascular and endothelial dysfunction, small vessel disease, diffuse atherosclerosis, and inflammation have been held responsible in the etiology of coronary slow flow. It is also thought to be a reflection of a systemic slow-flow phenomenon in the coronary arterial tree. Case Report A 44-year-old man presented with chest pain causing...

he enigma of angina in the absence of significant epicardial coronary artery disease (CAD) has puzzled cardiologists since the advent of invasive coronary angiography. Indeed, an early paper by Likoff et al1 was entitled ‘Paradox of normal selective coronary angiograms in patients considered to have unmistakable coronary heart disease’ and described 15 women with angina, a positive exercise str...

Received: August 13, 2015. Revision received: August 13, 2015. Accepted after revision: August 17, 2015. Bangkok Med J 2015;10:22-26. E-journal: http://www.bangkokmedjournal.com Abstract Angina pectoris and abnormally slow contrast propagation into the unobstructed coronary artery, the so-called coronary slow fl ow (CSF) phenomenon was fi rst recognized four decades ago but the etiology remaine...

Slow coronary flow is an angiographic phenomenon characterized by delayed opacification of vessels in the absence of any evidence of obstructive epicardial coronary disease. In this article, we present serious clinical manifestations of extremely slow coronary flow in two hypertensive patients with preserved ejection fraction in echocardiographical examination: a 57 year-old woman with acute co...

Zehir et al. (1) found that Tpe (T-wave peak to end time) Interval and Tpe/QT ratio were prolonged in patients with Coronary Slow Flow Phenomenen (CSFP), published in this issue of Anatol J Cardiol. The coronary slow flow phenomenon is an angiographic finding that is characterized by slow progression of the contrast seen during coronary angiography. It can be present in a diverse population fro...

Intravascular ultrasound imaging can detect intimal thickening and is suitable for detection of early atherosclerosis, which cannot be detected by conventional angiography. The aim of the present study was to investigate the epicardial coronary morphology and intracoronary pressure in relation to slow coronary flow (SCF). The study population consisted of 19 patients with SCF [11 (57.9%) female...

ST-segment depression is commonly seen in patients with acute coronary syndromes. Most authors have attributed it to transient reductions in coronary blood flow due to nonocclusive thrombus formation on a disrupted atherosclerotic plaque and dynamic focal vasospasm at the site of coronary artery stenosis. However, ST-segment depression was never reproduced in classic animal models of coronary s...

Coronary slow flow is a rare, clinically important entity observed in acute coronary syndrome. The pathophysiological mechanism is not fully elucidated. We investigated patients with chest pain who had angiographic features consistent with the coronary slow flow. One hundred ten patients were included. Electrocardiography, echocardiography, and angiography results were retrospectively noted. Th...

Inadequate coronary vasodilator reserve, 1 luminal narrowing of coronary capillaries, and systolic compression of the intramyocardial small arteries are considered to contribute towards myocardial ischaemia in patients with hypertrophic cardiomyopathy (HCM). Previously, abnormal phasic coronary flow velocity pattern in the left anterior descending coronary artery (LAD) in patients with HCM, whi...