نتایج جستجو برای: small colony variant

تعداد نتایج: 928714  

Journal: :Journal of clinical microbiology 2008
Michael Schneider Kathrin Mühlemann Sara Droz Sabine Couzinet Carmen Casaulta Stefan Zimmerli

During a 3-month period, small-colony variant phenotypes of both Staphylococcus aureus and Pseudomonas aeruginosa were isolated from respiratory secretions of 8.2% and 9.2%, respectively, of 98 patients with cystic fibrosis, particularly those with advanced pulmonary disease and prolonged antibiotic exposure.

Journal: :Antimicrobial agents and chemotherapy 2008
Brian T Tsuji Christof von Eiff Pamela A Kelchlin Alan Forrest Patrick F Smith

The in vitro bactericidal activities of vancomycin against Staphylococcus aureus hemB mutants displaying the small-colony-variant phenotype and their parental strains were evaluated. Vancomycin killing activities against hemB mutants were markedly attenuated, demonstrating approximately 50% less effect, a result which was well described by a Hill-type pharmacodynamic model.

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