نتایج جستجو برای: smallconductance calciumactivated potassium channels

تعداد نتایج: 203022  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2004
Mary D Womack Carolyn Chevez Kamran Khodakhah

Cerebellar Purkinje neurons fire spontaneously in the absence of synaptic transmission. P/Q-type voltage-gated calcium channels and calcium-activated potassium channels are required for normal spontaneous activity. Blocking P/Q-type calcium channels paradoxically mimics the effects of blocking calcium-activated potassium channels. Thus, an important function of the P/Q-type calcium channels is ...

Journal: :European journal of anaesthesiology 2001
P Friederich D Benzenberg B W Urban

BACKGROUND AND OBJECTIVE Interaction of intravenous anaesthetic agents with voltage-dependent potassium channels significantly correlates with clinical concentrations. If potassium channels were to play an important part in anaesthesia, one might expect different effects at the molecular level of those anaesthetics that show different clinical effects. Our aim was to analyse the interaction of ...

Journal: :The Journal of Cell Biology 2002
Matthew N. Rasband Eunice W. Park Dongkai Zhen Margaret I. Arbuckle Sebastian Poliak Elior Peles Seth G.N. Grant James S. Trimmer

Voltage-dependent potassium channels regulate membrane excitability and cell-cell communication in the mammalian nervous system, and are found highly localized at distinct neuronal subcellular sites. Kv1 (mammalian Shaker family) potassium channels and the neurexin Caspr2, both of which contain COOH-terminal PDZ domain binding peptide motifs, are found colocalized at high density at juxtaparano...

Journal: :iranian journal of allergy, asthma and immunology 0
changbiao chen department of respiratory, affiliated tongji hospital of tongji medical college, huazhong university of science and technology, wuhan 430030 and department of respiratory, hannan district people's hospital of wuhan, wuhan 430030, china. ran wang department of respiratory, the first affiliated hospital of anhui medical university, hefei 230001, china. sijing zhou department of occupational medicine, third people's hospital of hefei, hefei 230001, china. jianping zhao department of respiratory, affiliated tongji hospital of tongji medical college, huazhong university of science and technology, wuhan 430030, china. yongjian xu department of respiratory, affiliated tongji hospital of tongji medical college, huazhong university of science and technology, wuhan 430030, china.

bronchial asthma is the common chronic inflammatory disease and is characterized by chronic airway inflammation, airway remodeling, and airway hyperreactivity (ahr). aim of this study was to investigate the effects of mitochondrial atp-sensitive potassium channels (mitokatp) on the proliferation and secretion of human airway smooth muscle cells (hasmcs). hasmcs were treated with the serum from ...

Journal: :Japanese Journal of Pharmacology 1997

Journal: :Acta Biochimica Polonica 2009

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