We analyzed the physicochemical characteristics of solid dispersions of pizotifen malate and povidone (Kollidon 12) at different proportions; we used X-ray diffraction, infrared spectrometry and differential scanning calorimetry (DSC) and tested the solubility of the solid dispersions in equilibrium. The results were compared with findings for physical mixtures with the same proportions. A soli...

Aim: To enhance the aqueous solubility of olanzapine by using the Solid dispersion technique. Solid dispersions of Olanzapine were prepared by the dispersion method using using PGS and SSG as carriers. Drug:carrier ratios such as 1:1, 1:2, 1:4, 1:6, 1:8 and 1:10 were tried for optimization. Characterization was done by phase solubility, in vitro release, saturation solubility, permeation, wetta...

Aim: To enhance the aqueous solubility of olanzapine by using the Solid dispersion technique. Solid dispersions of Olanzapine were prepared by the dispersion method using using PGS and SSG as carriers. Drug:carrier ratios such as 1:1, 1:2, 1:4, 1:6, 1:8 and 1:10 were tried for optimization. Characterization was done by phase solubility, in vitro release, saturation solubility, permeation, wetta...

osmotic dehydration, as a minimal processing method, has found increasingly wide prospects during the past few decades. this process involves mass transfer which is commonly modeled by applications of different procedures, mostly based on fick's law. in this research, we approached the modeling process by first obtaining experimental measurement of potato’s solid gain, water loss and moisture c...

The aim of this work is to chemically characterize olive tree prunings and use the material in hydrothermal and combustion processes. The influence of the hydrothermal treatment conditions, with and without acid catalyst, of the main fraction of olive tree prunings (stems with a diameter > 1 cm) (temperature 150 to 190oC, time 0 to 20 minutes after reaching the operation temperature, liquid/sol...

platinum extraction from different secondary sources has been experimentally tested by many researchers. in this article, dissolution of platinum in aqua-regia solution from two types of spent catalysts (reforming and nitric acid production) was kinetically studied. a variety of kinetic models for heterogeneous solid-liquid reactions, including homogeneous diffusion model, shrinking core model,...

Gas-phase velocity fluctuations in fixed particle beds and freely evolving suspensions are quantified using particle-resolved direct numerical simulation (PR-DNS). The flow regime corresponds to homogeneous gas-solid systems typically encountered in fluidized bed risers, with high solid to gas density ratio and particle diameter being greater than the dissipative length scales. The contribution...

The aim of the present numerical study is to analyze the conjugate natural convection heat transfer in a differentially heated square enclosure containing a conductive polygon object. The left wall is heated and the right wall is cooled, while the horizontal walls are kept adiabatic. The COMSOL Multiphysics software is applied to solve the dimensionless governing equations. The governing parame...