The long-term goal of this project is to develop multicomponent reactive transport models that can be used to accurately describe solute transport in temporally and spatially heterogeneous, organic-rich sediments. To achieve this goal, we have developed a model that can be used to obtain unbiased 1D quantitative descriptions of biologically-enhanced solute transport (bioirrigation due to macrof...

Selective extraction of a protein from a mixture can be accomplished using an adsorptive membrane and low displacement recuperative parametric pumping. Low displacement recuperative parametric pumping can lead to the preferential transport of an adsorbing solute and the rejection of nonadsorbing solutes by the adsorptive membrane. Using a protein mixture consisting of lysozyme and myoglobin, we...

In the present study, tried to examine the reactive solute relationships for transport and degradation processes through the rockfill media. By applying the analytical solution of reactive transport, the 1st to 3rd theoretical temporal moments have been extracted then, by using two methods of curve fitting and temporal moment matching, the coefficients of dispersion and degradation have been ex...

A finite-element approach was formulated, aimed at enabling an integrated study of mechanical and biochemical factors that control the functional development of tissue engineered constructs. A nonlinear biphasic displacement-velocity-pressure description was combined with advective and diffusive solute transport, uptake and biosynthesis. To illustrate the approach we focused on the synthesis an...

A "glymphatic system," which involves convective fluid transport from para-arterial to paravenous cerebrospinal fluid through brain extracellular space (ECS), has been proposed to account for solute clearance in brain, and aquaporin-4 water channels in astrocyte endfeet may have a role in this process. Here, we investigate the major predictions of the glymphatic mechanism by modeling diffusive ...

The transport of macromolecules across the renal glomerular capillary wall has been described theoretically using flux equations based on (a) restricted transport through small pores, and (b) the Kedem-Katchalsky formulation. The various assumptions and limitations inherent in these two approaches are discussed. To examine the coupling between macromolecular solute transport and the determinant...

Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed 'glymphatic' clearance mechanism additionally suggests that aquaporin-4 (AQP4) water channels facilitate convective transport through brain parenchyma. Here, the major experimental underpinnings of the g...

At the ultrastructural level, epithelia performing solute-linked water transport possess long, narrow channels open at one end and closed at the other, which may constitute the fluid transport route (e.g., lateral intercellular spaces, basal infoldings, intracellular canaliculi, and brush-border microvilli). Active solute transport into such folded structures would establish standing osmotic gr...

Based on a comprehensive field study conducted at the Miinchehagen waste disposal site, the groundwater flow and solute transport characteristics of fissured argillites rocks are described. Particularly recent multi-tracer experiments and supplementary laboratory diffusion and batch sorption experiments are presented. The fissured rock behaves as an anisotropic homogeneous continuun with respec...