The present study demonstrates the use of mixed co solvency in the enhancement of solubility and estimation of ketoprofen, practically water insoluble dug and thus precludes the use of organic solvents. The selected solubilizers were sodium citrate (15%), PEG 400 (8%) and polyvinyl pyrolidine (7%). Beer’s law was obeyed in the concentration range of 2-20μg/ml at wavelength of 256nm. The solubil...

This study aims to observe the effect of Auditor switching, profitability, solvency, auditor quality on audit delay and firm size in its ability moderate solvency LQ 45 companies listed IDX 2016-2018 period as research samples. is a quantitative with multiple linear regression analysis technique special application linear, namely Moderated Regression Analysis (MRA) measure moderating variable. ...

The basic components of the risk/return model applicable to insurance consist of underwriting return, investment return and leverage. A pricing approach is presented to deal with underwriting and investment risk, guided by basic risk/return principles, which addresses the policyholder and shareholder perspectives in a consistent manner. A methodology to determine leverage is also presented, but...

New risk-based solvency requirements for insurance companies across European markets have been introduced by Solvency II and will come in force from 1 January 2016. These requirements, derived by a Standard Formula or an Internal Model, will be by far more risk-sensitive than the required solvency margin provided by the current legislation. In this regard, a Partial Internal Model for Premium R...

We relate the maximum semidefinite and linear extension complexity of a family of polytopes to the cardinality of this family and the minimum pairwise Hausdorff distance of its members. This result directly implies a known lower bound on the maximum semidefinite extension complexity of 0/1-polytopes. We further show how our result can be used to improve on the corresponding bounds known for pol...

Validity • Independent blind comparison with a gold standard or follow-up of those not receiving the gold standard test? Yes, the cone biopsy was the gold standard. • Was “normal” defined? Yes, according to the Bethesda system. • Appropriate spectrum of disease? Not to assess technology for screening. This was a high-risk sample, and the sensitivity and specificity likely differs from a screeni...