Hawaii established a Clinical Research Center with collaboration from the University of Hawaii Pacific Biomedical Research Center, the John A. Burns School of Medicine and Kapiolani Health via a five year award from the Research Centers in Minority Institutions of the National Institutes of Health. Support offered includes consultative services for protocol design; epidemiological and biostatis...

During April 2009-June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant. Most patients with oseltamivir-resistant infections were severely immunocompromised (76%) and had received oseltamivir before specimen collection (89%). No evidence was found for community circulation of resistant viruses; only 4 (unlinked) pat...

closely related to a genotypic group of viruses isolated from the eastern United States and two Caribbean countries from 1999 to 2001 (6). Results from our phylogenetic analysis showed that Thess1/GRE99, as well as strains G432/GER99 and 6423/PV/ITA97 (and the United Kingdom 1999 strains), were clustering with strains FRI/BAH97 (accession no. AY326359), isolated in 1997 from the Bahamas, and DE...

Multiorgan pathology is a common finding during the diagnostic work-up of complex medical diseases in small animals. Collection of cytologic or biopsy samples from several abdominal organs can give the clinician crucial information in guiding therapy. Although many modalities are available for sample collection, laparoscopic and laparoscopic-assisted techniques offer a minimally invasive approa...

A simple, inexpensive, non-invasive method for urine collection was used in 28 consecutive infants for periods of 48 hours (n = 10) and 72 hours (n = 18). The incidence of urine collector detachment was low on the first and second days (< 4%) and increased significantly on the third day (28%). Volume of urine leaked was < 4% of the total volume collected daily. This method is applicable to both...

We report on the use of simulation modeling for redesigning phlebotomy and specimen collection centers (or patient service centers) at a medical diagnostic laboratory. Research was performed in an effort to improve patient service, in particular to reduce average waiting times as well as their variability. Discrete-event simulation modeling provided valuable input into new facility design decis...