introduction: spect is a diagnostic imaging technique the main disadvantage of which is the existence of poisson noise. so far, different methods have been used by scientists to improve spect images. the wavelet transform is a new method for de-noising which is widely used for noise reduction and quality enhancement of images. the purpose of this paper is evaluation of noise reduction in spect ...

UNLABELLED In SPECT using high-energy photon-emitting isotopes, such as (131)I, parallel-hole collimators with thick septa are required to limit septal penetration, at the cost of sensitivity and resolution. This study investigated a parallel-hole collimator with cone-shaped holes, which was designed to limit collimator penetration while preserving resolution and sensitivity. The objective was ...

UNLABELLED (111)In-Capromab pendetide imaging is indicated for postprostatectomy patients at risk for residual or recurrent disease. However, this study is complicated by relatively long times for tumor uptake and background washout that require imaging to be performed several days after radiopharmaceutical administration. In addition, (111)In-capromab pendetide demonstrates uptake in normal st...

The modeling of 3D Compton scatter in SPECT is complicated by the use of a variety of collimator geometry. To date, effective and efficient modeling of 3D Compton scatter in parallel-beam SPECT has been made possible by Frey and Tsui [1], Zeng et al [2], and Bai et al [3]. For fan-beam and cone-beam SPECT, the model in [3] can effectively model first order 3D Compton scatter. But for varying-fo...

background: obtaining high quality images in single photon emission tomography (spect) device  is the most important goal in nuclear medicine. because if image quality is low, the possibility of making a mistake in diagnosing and treating the patient will rise. studying effective factors in spatial resolution of imaging systems is thus deemed to be vital. one of the most important factors in sp...

The INSERT is the world’s first clinical SPECT-MRI brain imaging system based on scintillation detectors with a silicon photomultiplier readout. Here, we demonstrate its use within MRI environment for time. Using standard transmit-receive head coil, and an appropriate selection of custom sequence (GRE), overcome mutual interference. bulky 50kg tungsten collimator introduce magnetic field inhomo...

introduction: monte carlo (mc) is the most common method for simulating virtual spect projections. it is useful for optimizing procedures, evaluating correction algorithms and more recently image reconstruction as a forward projector in iterative algorithms; however, the main drawback of mc is its long run time. we introduced a model based method considering the effect of body attenuation and i...

Multi-slat prompt-gamma camera is a promising tool for range monitoring during proton therapy. We report the results of comprehensive simulation study analyzing precision which possible to reach with this in determination position distal edge Bragg peak. For first time we include optical photons. The beam (single pencil beam, 130 MeV, 10 ns bunch period, total 1·108 protons) interacting polymet...

UNLABELLED The aim of this study was to evaluate differences in dopamine transporter SPECT images among different SPECT/CT devices and to determine the most appropriate region of interest (ROI) for semiquantitative evaluation. METHODS An anthropomorphic striatal phantom was filled with (123)I solutions of different striatum-to-background radioactivity ratios. Data were acquired using 2 SPECT/...