The voltammetric behavior of isradipine was studied using direct current (DC(t)), differential-pulse (DPP) and alternating current (AC(t)) polarography. Isradipine exhibited well-defined cathodic waves over the whole pH range in Britton-Robinson buffer (BRb). At pH 5, the analytical pH, the diffusion-current constant (Id) was 8.27+/-0.52. The current-concentration plots were rectilinear over th...

in this study, a rapid, simple and sensitive ion mobility spectrometry (ims) method with corona discharge as ionization source was described for the morphine determination in human urine. morphine was extracted and purified from urine samples using solid phase extraction procedure with c18 column. it can offer the clean extracts which no extra peaks were observed in ims. under operating experim...

An analytical method for the simultaneous determination of glyphosate (GLY) and its main derivative, aminomethyl-phosphonic acid (AMPA), in human urine has been developed using gas chromatography coupled to tandem mass spectrometry (MS/MS) operated multiple reaction monitoring mode (MRM). Sample preparation involved dilution with water derivatization a mixture trifluoroacetic anhydride trifluor...

The anodic polarographic behaviour of josamycin (a macrolide antibiotic) has been studied using direct current (DC(t)) polarography and differential pulse polarography (DPP). In Britton-Robinson buffers (BRb) josamycin exhibited well-defined anodic polarographic waves in the pH range 2-8. In BRb of pH 6, the diffusion-current constant was 1.62 microA mmol(-1) (n = 6). The current-concentration ...

The paper describes the use of native β-cyclodextrin (CD) for modification silver nanoparticles (AgNPs) in order to improve determination anticancer drug methotrexate (MTX) using surface-enhanced Raman spectroscopy (SERS). A control experiment with unmodified AgNPs showed that strong SERS signal MTX can only be achieved alkaline media. However, competitive interactions and background human body...

Agricultural workers are exposed to folpet, but biomonitoring data are limited. Phthalimide (PI), phthalamic acid (PAA), and phthalic acid (PA) are the ring metabolites of this fungicide according to animal studies, but they have not yet been measured in human urine as metabolites of folpet, only PA as a metabolite of phthalates. The objective of this study was thus to develop a reliable gas ch...