نتایج جستجو برای: spiro indole
تعداد نتایج: 12558 فیلتر نتایج به سال:
Five new spiro[indoline-3,3′-indolizine]s have been synthesized with high regio- and stereospecificity in one-pot three-component reactions between a substituted indole-2,3-dione, ( S )-pipecolic acid trans -3-benzoylacrylic acid, subsequently characterized using combination of elemental analysis, IR 1 H 13 C NMR spectroscopy, mass spectrometry crystal structure analysis. (1′ SR ,2′ ,3 RS ,8a′ ...
Infections are one of the most important causes of death, disability and inappropriate conditions for millions of people around the world. Therefore, the development in prognosis, prevention and treatment of infectious diseases made a considerable progress in designing and synthesis of new antimicrobial drugs. Nowadays, due to the increase in microbial resistance, discovery of new compounds wit...
Infections are one of the most important causes of death, disability and inappropriate conditions for millions of people around the world. Therefore, the development in prognosis, prevention and treatment of infectious diseases made a considerable progress in designing and synthesis of new antimicrobial drugs. Nowadays, due to the increase in microbial resistance, discovery of new compounds wit...
Radical-radical cross coupling reactions of photoexcited 9-fluorenones have been accomplished for the first time, leading to the synthesis of 9-alkyl, pyrollidinyl and spiro-THF derivatives of 9-fluorenones. The method also reveals, for the first time, the behaviour of ketyl radicals in decarboxyaltive alkylation and ring expansion reactions.
In a sustained search for novel ?-amylase inhibitors the treatment of type 2 diabetes mellitus (T2DM), we report herein synthesis series nineteen rhodanine-fused spiro[pyrrolidine-2,3?-oxindoles]. They were obtained by one-pot three component [3 + 2] cycloaddition stabilized azomethine ylides, generated in situ condensation glycine methyl ester and cyclic ketones 1H-indole-2,3-dione (isatin), w...
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