The lung parenchyma provides a maximal surface area of blood-containing capillaries that are in close contact with a large surface area of the air-containing alveoli. Volume and surface area of capillaries are the classic stereological parameters to characterize the alveolar capillary network (ACN) and have provided essential structure-function information of the lung. When loss (rarefaction) o...

BACKGROUND Behavioural and anatomical studies in schizophrenia have pointed to cerebellar involvement. AIMS To provide stereological estimations of volumes and cell number in the cerebella of people with schizophrenia and a control group using post-mortem material. METHOD Stereological methods were applied to cerebella taken from eight male patients with a DSM-III diagnosis of chronic schiz...

This is a short overview on synaptic coverage of the dendritic tree in the superior cervical ganglion of capybara based on the application of the electronimmunocytochemistry of synaptophysin combined with stereological tools. It is shown how to estimate the surface coverage of dendrites by postsynaptic apposition zones and how to perform a model-based stereological estimate of the numbers and s...

The 2-D stereology can be used advantageously in the case of muscle cross sections stained by routine histochemical and immunocytochemical methods, such as mATPase reaction, when the quality of the image is often not sufficient for using image analysis techniques without considerable individual intervention. Other advantages of stereological methods in muscle morphometry are that measurements a...

Brain balance changes have been recognised in migraine, but cerebellar function between or during attacks has been assessed only in a few studies. Previous studies have indicated that migraine affects cerebellar function. In the present study we aimed to evaluate the hemicerebellar volume changes of patients with migraine without aura (MWoA). Volumetric changes of cerebellar hemispheres were ev...

The aim of this paper is to present a new projective stereological method that enables to estimate the size and the shape of a three-dimensional convex object from measurements only made on its two-dimensional projections. To do so, some geometrical and morphometrical measurements on the projected shadows of the three-dimensional convex object are done and the value of the three-dimensional con...

The aim of this study was to examine the effect of experimental hyperprolactinemia on the stereological parameters of porcine adrenal cortex. In cyclic sows, after preovulatory luteinizing hormone (LH) peak, porcine prolactin (PRL, 0.3 mg) or saline were administered i.v. for 48 h at 2 h intervals. Next sows were slaughtered and adrenal glands were dissected. Stereological analysis of the left ...

PURPOSE To develop a stereological comparison between right (RV) and left ventricle (LV) myocardium during the third human gestational trimester. METHODS Five human fetal hearts of the third trimester provided representative samples of 5 RV myocardium and 4 LV myocardium. The material was fixed in 10% buffered formaldehyde, and processed through routine methods. Fifteen microscopic fields wer...

Stereological methods for serial sections traditionally assume that the sections are exactly equally spaced. In reality, the spacing and thickness of sections can be quite irregular. This may affect the validity and accuracy of stereological techniques, especially the Cavalieri estimator of volume. We present a new formula for the accuracy of the Cavalieri estimator that includes the effect of ...