Pemphigus vulgaris (PV) is an autoimmune blistering disease affecting the skin and mucosa. It clinically presents as painful erosions, mainly in oral cavity, flaccid blisters erosions on skin. Steven-johnson syndrome/toxic epidermal necrolysis (SJS/TEN) a severe mucocutaneous drug hypersensitivity reaction characterized by painful, dusky, erythematous eruptions that often progress to blisters, ...

elevated serum level of bilirubin is a common manifestation which is occurred in several diseases. hyperbilirubinemia can manifest either conjugated or unconjugated. conjugated or direct hyperbilirubinemia usually are caused by hepatocellular diseases or cholestatic liver diseases. merely conjugated hyperbilirubinemia is the main manifestation of two congenital syndromes, including dubin-johnso...

Background Stevens-Johnson syndrome (SJS) is one of potentially fatal disorders that often occur after taking certain types of medication. There are reports of this disease after some infections. This paper presents the case of a young boy with idiopathic Stevens-Johnson syndrome. Case Report A six-year-old male patient with complaint of fever and skin lesions was transferred to emergency depar...

Yarden Livnat, Steven G. Parker, Christopher R. Johnson University of Utah 47.

Tuberculosis (TB) still becomes a significant health problem in Indonesia. The first-line anti-tuberculosis drug (ATD) is the most effective TB drug, but it can have some side effects. One of them allergic skin reactions that affect patient's compliance. Allergic due to ATD are found 4-6% cases and third frequent effect after gastrointestinal liver function disorder. All cause reactions. be mil...

Toxic epidermal necrolysis (TEN) is a rare, severe adverse drug reaction. Steven-Johnson syndrome (SJS) represents the milder end of the spectrum. The exact pathogenesis of TEN and SJS is still unknown and many drugs, including prednisolone, cyclosporin and intravenous immunoglobulin (IVIG), have been used in an attempt to halt the disease process. The use of IVIG in particular is controversial...