Aims—To understand the immunopathogenesis of the corneal conjunctivalisation in Stevens–Johnson syndrome. Methods—Conjunctivalised corneas from five patients with Stevens–Johnson syndrome were studied immunohistochemically for several cell surface antigens and two cytokines. Chemical injury specimens were also studied. Results—In all cases, immunohistochemistry revealed LFA-1, CD4, CD8, and CD6...

Stevens-Johnson syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome in children. Herein, we report a co-amoxiclav-induced Stevens-Johnson syndrome occurring in an 18...

Figure 1. Anteroposterior view of the trunk with coa-lescing vesicobullous lesions.

Stevens-Johnson syndrome is a severe disease which is characterized by fever and mucocutaneous lesions. It has also been described as a small airway compromise in the form of bronchiolitis obliterans. We report a 22-year-old male patient with Stevens-Johnson syndrome due to antibiotic and antiepileptic drug treatment for brain abscess. After the improvement of mucocutaneous lesions, he went to ...

The study of the pigment apparatus (chlorophylls, carotenoids) and flavonoids will allow to reveal plants adaptation mechanisms, which subsequently can be used in ecological biochemical studies. purpose is determine content photosynthesis pigments phytomass hydroponically grown garden sage (Salvia officinalis L.) compared with open soil. Two varieties were studied: ‘Dobrinya’ ‘Kubanets’ from tw...

Adverse drug reactions occur in about 0.3 to 7% of all hospital admissions and are associated with high morbidity and mortality. Their presentation varies from mild rashes to severe reactions such as StevensJohnson syndrome (SJS). Steven Johnson's Syndrome is rare, serious systemic disorder involving the skin and mucous membranes. Stevens-Johnson syndrome is commonly associated with adverse dru...