نتایج جستجو برای: stigmasterol

تعداد نتایج: 625  

2013
Kingkan Bunluepuech Chatchai Wattanapiromsakul Fameera Madaka Supinya Tewtrakul

A stem ethanol extract of Bauhinia strychnifolia and its compounds were investigated for their anti-HIV-1 integrase (IN) and anti-allergic activities. From bioassay-guided isolation, five compounds including quercetin (1), 3,5,7,3',5'pentahydroxyflavanonol-3-O--L-rhamnopyranoside (2), 3,5,7-trihydroxychromone-3--L-rhamnopyranoside (3) and a mixture of -sitosterol (4) and stigmasterol (5) wer...

Journal: :Plant physiology 1989
D J Brown F M Dupont

Membrane fractions enriched in endoplasmic reticulum (ER), tonoplast and Golgi membranes (TG) and plasma membranes (PM) were prepared from barley (Hordeum vulgare L. cv CM 72) roots and the lipid compositions of the three fractions were analyzed and compared. Plants were grown in an aerated nutrient solution with or without 100 millimolar NaCl. Each membrane fraction had a characteristic lipid ...

Journal: :Journal of natural products 1998
L Alvarez M Y Rios C Esquivel M I Chávez G Delgado M I Aguilar M L Villarreal V Navarro

Two new cytotoxic isoflavans, (3S)-7-hydroxy-2',3',4',5', 8-pentamethoxyisoflavan (1) and (3S)-3',7-dihydroxy-2',4',5', 8-tetramethoxyisoflavan (2), were isolated from the bark and trunks of Eysenhardtia polystachya (Leguminosae), together with the known constituents stigmasterol, isoduartin, cuneatin, 7-hydroxy-2',4', 5'-trimethoxyisoflavone, and 3,4-dimethoxy-8, 9-(methylenedioxy)pterocarpan....

Journal: :Bioorganic & medicinal chemistry 2007
Javier A Ramírez Andrea C Bruttomesso Flavia M Michelini Sofía L Acebedo Laura E Alché Lydia R Galagovsky

In a previous work our group showed that some synthetic stigmastanes may play a role in immune-mediated inflammation. In this paper we report the syntheses of a series of new steroidal compounds derived from dehydroepiandrosterone and stigmasterol, and the evaluation of their in vitro inhibitory activity of the TNF-alpha production by macrophages. A preliminary qualitative structure-activity re...

Journal: :Molecules 2012
Sakina Saadawi Juriyati Jalil Malina Jasamai Ibrahim Jantan

Acetylmelodorinol, chrysin and polycarpol, together with benzoic acid, benzoquinone and stigmasterol were isolated from the leaves of Mitrella kentii (Bl.) Miq. The compounds were evaluated for their ability to inhibit prostaglandin E₂ (PGE₂) and thromboxane B₂ (TXB₂) production in human whole blood using a radioimmunoassay technique. Their inhibitory effect on platelet activating factor (PAF) ...

Journal: :The American journal of clinical nutrition 2014
Annika Mutanen Markku J Nissinen Jouko Lohi Päivi Heikkilä Helena Gylling Mikko P Pakarinen

BACKGROUND Increased serum concentrations of plant sterols, including stigmasterol, during parenteral nutrition (PN) have been linked with serum biochemical signs of intestinal failure-associated liver disease (IFALD), whereas clinical data on their correlation to histologic liver injury have been limited. OBJECTIVE We studied interrelations between serum noncholesterol sterols and histologic...

Journal: :Steroids 2015
Blanca Barriuso Diana Ansorena Candelaria Poyato Iciar Astiasarán

The characteristics of the lipid matrix surrounding sterols exert a great influence in their thermal oxidation process. The objective of this work was to assess the oxidation susceptibility of equal amounts of cholesterol and stigmasterol within a sunflower oil lipid matrix (ratio 1:1:200) during heating (180°C, 0-180min). Remaining percentage of sterols was determined and seven sterol oxidatio...

Journal: :Molecules 2012
Soek Sin Teh Gwendoline Cheng Lian Ee Siau Hui Mah Yang Mooi Lim Mawardi Rahmani

An investigation on biologically active secondary metabolites from the stem bark of Mesua beccariana was carried out. A new cyclodione, mesuadione, along with several known constituents which are beccamarin, 2,5-dihydroxy-1,3,4-trimethoxy anthraquinone, 4-methoxy-1,3,5-trihydroxyanthraquinone, betulinic acid and stigmasterol were obtained from this ongoing research. Structures of these compound...

Journal: :Acta pharmaceutica 2004
Kamrun Nahar Asha Rasheduzzaman Chowdhury Choudhury M Hasan Mohammad A Rashid

Two known steroids, stigmasterol and 6b-hydroxystigmasta-4,22-dien-3-one (1) and two unusual polyketides, cis-4-hydroxymellein (2) and trans-4-hydroxymellein (3) were isolated from the stem bark of Uvaria hamiltonii. The structures of the compounds were elucidated independently by high-resolution 2D-NMR techniques and confirmed by comparison with previously reported values.

Journal: :Bioscience, biotechnology, and biochemistry 2004
Toru Uekawa Ken Ishigami Takeshi Kitahara

Chenodiol is an important bile acid widely used for gallstone dissolution and cholestatic liver diseases. We succeeded in a short-step synthesis of chenodiol, starting from the safer phytosterol, stigmasterol.

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