Details in the fermentation of oxytetracycline in a synthetic medium with Streptomyces rimosus have been presented. In these studies, an organic nitrogen source was shown to be essential for the production of significant amounts of antibiotic activity. Of the amino acids tested, aspartic acid, proline, threonine, valine, and beta-alanine were utilized well for both growth and antibiotic product...

Oxytetracycline, one of the tetracycline family, is a broadspectrum antibiotic produced by different species of Streptenryces, namely Streptomyees rimosus, Streptonryces capuensis, Streptomyces henetus, and Struptomyces platensis (Finlay et al,i)), The antibiotic is active on Gram-pesitive and negative bacteria, spirochetes, rickettsiae, nd some viruses, Many workers2"i4) have studied factors a...

The utilization of actinomycetes as potential soybean (Glycine max (L.)) co-inoculants was evaluated. Soil samples from Carbondale and Belleville, Ill., were used to inoculate pre-germinated soybean plants to determine antibiotic sensitivity in the native Bradyrhizobium japonicum population. Sensitivity was in the order kanamycin > tetracycline > oxytetracycline > rifampicin > neomycin. Antagon...