نتایج جستجو برای: streptozotocin induced diabetes

تعداد نتایج: 1247110  

2013
Pedro Macedonio García-López

Objective: The high global incidence of type 2 diabetes has challenged researchers to establish animal models that resemble the chronic stage observed in type 2 diabetes patients. One such model is induced by neonatal streptozotocin (n-STZ) administration to rat pups at 0, 2, or 5 days after birth. In this study, we assessed Ins-1 gene expression and tissue insulin levels as well as serum conce...

Background: All-trans retinoic acid (ATRA) has a variety of biological activities, including immunomodulatory action in a number of inflammatory and autoimmune diseases. The purpose of this study was to investigate the effects of all-trans retinoic acid on the treatment of autoimmune diabetes in mice and its effects on expressions of Peroxisome Proliferator-Activated Receptor gamma (PPARγ...

A Eidi A Saeidi M Eidi S Oryan

Diabetes mellitus is considered a serious endocrine syndrome. The prevalence of diabetes mellitus in the general population is greater than 6%. Many herbal medicines have been recommended for the treatment of diabetic. The present study was carried out to investigate the effect of the alcoholic extract seeds of Coriandrum sativum L. on blood glucose in streptozotocin-induced diabetic rats. The ...

A Eidi A Saeidi M Eidi S Oryan

Diabetes mellitus is considered a serious endocrine syndrome. The prevalence of diabetes mellitus in the general population is greater than 6%. Many herbal medicines have been recommended for the treatment of diabetic. The present study was carried out to investigate the effect of the alcoholic extract seeds of Coriandrum sativum L. on blood glucose in streptozotocin-induced diabetic rats. The ...

حب‌نقی , رحیم , دلیرژ , نوروز , ملکی‌فرد , فرین , ملکی‌نژاد , حسن ,

Background & Aims: It has been shown that some drugs such as Pentoxifylline (PTX) have immunomodulatory and anti-inflammatory activity that might represent a potential preventive therapy for autoimmune diseases. The purpose of this study was to investigate the therapeutic effects of pentoxifylline on the treatment of autoimmune diabetes in mice and its effects on expressions of peroxisome proli...

Journal: :International Journal of Ayurvedic Medicine 2023

Guizotia abyssinica Cass. widely grown plant of southern India, seed oil which are said to be healthy source oil. Diabetes mellitus is a metabolic disorder affecting major population worldwide. Nutritive oils and fats essential in current scenario. Hence antidiabetic property Cass tested Streptozotocin induced diabetes Wistar albino Rats. Materials methods: Test drug collected, authenticated, p...

Journal: :Journal of Education, Health and Sport 2021

Introduction. There are evidence that oxidative stress is involved in the pathogenesis of acute generalized peritonitis and diabetes mellitus.The aim study was to examine levels products lipid peroxidation antioxidants rats with experimental against background streptozotocin-induced diabetes.Material methods. The experiment performed on 66 adult white male weighing 220-300 g. Diabetes mellitus ...

Journal: :Current perspectives on medicinal and aromatic plants 2021

The antidiabetic effect of Hunteria umbellata extracts (aqueous and methanol) on hematological, lipid profile biochemical parameters in streptozotocin-induced diabetes female wistar rats was studied. phytochemical screening the seed determined using standard chemical methods. Twenty five (25) weighing between 117g 170g were shared into (5) groups animals per group for physiological studies. All...

Journal: :Proceedings of the National Academy of Sciences 1983

Journal: :Diabetes 2021

Recent evidence suggests that melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs), a neuronal class regulating non-image forming (NIF) vision and generally thought to be injury resistant, are dysfunctional in certain neurodegenerative diseases. Although disrupted NIF visual functions have been reported patients animals with diabetes, it remains controversial wheth...

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