Osteochondral lesions of the talus that have previously undergone surgical management or involve the shoulder region of the talus require methods other than microfracture for treatment. For those lesions that have failed microfracture and do not involve the shoulder of the talus, osteochondral autologous transfer is our preferred treatment of choice. Perpendicular access to the lesion, often by...

BACKGROUND Post-concussion syndrome (PCS) associated with mild traumatic brain injury (MTBI) can cause long-lasting disabilities. Magnetic resonance imaging (MRI) evaluation in these patients may demonstrate structural lesions that correlate with functional deficits on neuropsychological testing. However, little is known about the significance of the relationship between structural lesions on M...

This is the presentation of one year prospective study on the anatomical structural lesions in ocular traumas with their visual outcome among those cases admitted and treated at Nepal Eye Hospital, Kathmandu. The changing life style of the people and environmental changes around with the changing nature of the causative objects on eye injuries have been observed for causing more serious structu...

Twin pregnancies are at increased risk of complications and adverse outcome compared to singletons. A significant contribution to higher morbidity and mortality seen in monochorionic twins is made by cardiac complications. Abnormal cardiac development in monochorionic pregnancies can be divided into primary structural cardiac lesions (structural cardiac anomalies unrelated to the existence of T...

The eukaryotic global genomic nucleotide excision repair (GG-NER) pathway is the major mechanism that removes most bulky and some nonbulky lesions from cellular DNA. There is growing evidence that certain DNA lesions are repaired slowly or are entirely resistant to repair in cells, tissues, and in cell extract model assay systems. It is well established that the eukaryotic DNA lesion-sensing pr...

The treatment of vascular lesions of the tongue is a very challenging procedure since the maintenance of the lingual tissue is of critical importance. Numerous treatment options have been described in literature but the Nd:YAG Laser appears to be one of the safest therapeutic options. We described a successful treatment of vascular lesions of the tongue with an excellent clinical result after o...

BACKGROUND AND PURPOSE Stroke is a major cause of cognitive impairment and dementia in adults, however the role of the ischemic lesions themselves, on top of other risk factors known in the elderly, remains controversial. This study used structural equation modeling to determine the respective impact of the new ischemic lesions' volume, preexisting white matter lesions and white matter integrit...