Weaver and Neill (1954) reported abnormal excretions of taurine, sometimes accompanied by over-excretion of lysine, cystine, and leucine, in the urine of five patients suffering from pernicious anaemia. In one patient with subacute combined degeneration of the spinal cord in whom the blood picture was normal, they found that taurine alone was excreted in abnormal quantities. After treatment wit...

SUBACUTE combined degeneration of the spinal cord in nutritional vitamin B12 deficiency states, though a rare complication, has been reported several times (Badenoch, 1954; Wokes, 1956; Smith, 1962; Connor & Pirola, 1963; Riley, 1966; Verjaal & Timmermans, 1967), and its association with veganism (vegans are people who exclude all forms of animal products from their diet) has been duly stressed...

Deficiency of Vitamin B12 can have many neurologic sequelae including periperhal neuropathy, visual disturbances, mood and memory changes and subacute combined degeneration (SCD) of the spinal cord1. Macrocytic anemia is also a common finding of B12 deficiency allowing the clinician to arrive at a diagnosis, however neurologic symptoms can be present even in the absence of hematologic changes. ...

Several studies have reported a possible link between antiaquaporin- 4 antibody and vitamin B12 deficiency in neuromyelitis optica spectrum disorder (NMOSD). Bilaterally symmetric hyperintense signals on magnetic resonance imaging (MRI) of the posterior columns, called inverted V sign, are characteristic feature subacute combined degeneration associated with deficiency. We report patient anti-a...

Deficiency of Vitamin B12 can have many neurologic sequelae including periperhal neuropathy, visual disturbances, mood and memory changes and subacute combined degeneration (SCD) of the spinal cord1. Macrocytic anemia is also a common finding of B12 deficiency allowing the clinician to arrive at a diagnosis, however neurologic symptoms can be present even in the absence of hematologic changes. ...