Posttraumatic stress disorder (PTSD) is a serious and global problem, a psychiatric disorder that frequently occurs with different comorbidities, and is associated with a high suicide rate. Pathophysiologically, both PTSD and suicidal behavior are related to disturbances in the central serotonergic system. Serotonin (5-hydroxytryptamine, 5-HT) controls emotional behavior, anxiety, impulsivity a...

OBJECTIVES Prior research has found that insomnia symptoms and nightmares are associated with suicidal ideation, suicide attempts, and death by suicide. However, to the best of our knowledge, no research has examined the relation between insomnia symptoms, nightmares, and suicidal ideation in older adults. The current project aimed to fill this void by investigating the relation between insomni...

Background: There are many controversies about the frequency and burden of suicidality in patients with Obsessive-Compulsive Disorder (OCD). Objectives: This study was done to determine the prevalence and risk factors of current suicidal ideations in patients with OCD. Materials & Methods: In this cross-sectional study, 258 outpatients with OCD (Yale-Brawn Obsessive Compulsive Scale, Y-BOCS ≥...

OBJECTIVE To measure changes in suicidal behaviours during 6 months of treatment with antidepressants. METHOD A group of depressed patients (n = 195) were assessed for suicidal behaviours in the 6 months prior to treatment. They were prospectively assessed for suicidal behaviours during 6 months of treatment with antidepressants. RESULTS Patients who made suicide attempts fell from 39 in th...

Objective: In patients with a history of suicidal depression, recurrence of depressive symptoms can easily reactivate suicidal thinking. This study investigated whether training in mindfulness, which is aimed at helping patients “decenter” from negative thinking, may help to weaken the link between depressive symptoms and suicidal cognitions. Method: Analyses were based on data from a recent ra...

OBJECTIVES To examine predictive power of psychache and life satisfaction on risks for suicidal ideation and suicide attempt among young people. DESIGN A cross-sectional study. SETTING Data were collected from an online survey in Wuhan, China. PARTICIPANTS 5988 university students from six universities were selected by a stratified cluster sampling method. PRIMARY AND SECONDARY OUTCOME ...

OBJECTIVE Schizophrenia has been associated with a high rate of suicide. This study investigates the prevalence of suicidal ideation in a population of inpatients with acute schizophrenia, together with the clinical parameters associated with suicidal thoughts. METHOD We assessed 93 schizophrenia patients. We matched subjects for age and sex and compared subjects with and without suicidal tho...

Suicidal behavior is a major health risk in psychiatric disorders, especially in affective and psychotic disorders. The neurobiology of suicidal behavior is still unclear. Suicidality has been related to a reduced cholesterol levels. The aim of this study was to evaluate serum cholesterol concentrations in suicidal and non-suicidal men suffering from persistent delusional disorder and in health...

OBJECTIVE In patients with a history of suicidal depression, recurrence of depressive symptoms can easily reactivate suicidal thinking. In this study, we investigated whether training in mindfulness, which is aimed at helping patients "decenter" from negative thinking, could help weaken the link between depressive symptoms and suicidal cognitions. METHOD Analyses were based on data from a rec...

Suicidal deaths and behavior in young people are major public health concerns. This study investigated the role of childhood sexual abuse (CSA), self-esteem, childhood gender nonconformity (CGN) and parental attachment in predicting suicidal ideation and attempts in 1203 (696 women) Turkish university students. Participants filled in a self-report questionnaire containing questions about suicid...