1a,25-Dihydroxyvitamin D3 [1,25(OH)2D3] concentrations are regulated by renal CYP27B1 for synthesis and CYP24A1 for degradation. Published plasma and tissue 1,25(OH)2D3 concentrations andmRNA fold change expression of Cyp24a1 andCyp27b1 following repetitive i.p. injections to C57BL/6 mice (2.5 mg 3 kg every 2 days for 4 doses) were fitted with a minimal and full physiologically-based pharmacoki...

Data mining is used to extract hidden information from large databases. In Peer-to-Peer context, a challenging problem is how to find the appropriate Peer to deal with a given query without overly consuming bandwidth. Different methods proposed routing strategies of queries taking into account the P2P network at hand. An unstructured P2P system based on an organization of Peers around Super-Pee...

The conventional data envelopment analysis (DEA) assumes that the inputs and outputs are real values. However, in many real world instances, some inputs and outputs must be in integer values. While integer-valued DEA models have been proposed, the current paper develops an integer-valued DEA super-efficiency model. Super-efficiency DEA models are known to have the problem of infeasibility. Rece...

The increasing interest in Peer-to-Peer systems (such as Gnutella) has inspired many research activities in this area. Although many demonstrations have been performed that show that the performance of a Peer-to-Peer system is highly dependent on the underlying network characteristics, much of the evaluation of Peer-to-Peer proposals has used simplified models that fail to include a detailed mo...

Super resolution technique was first proposed for enhancing the image resolution, and then it was expanded to video sequence for obtaining a higher resolution video from low resolution input. Recently, super-resolution based video coding has emerged as an important research topic as the image resolution increases rapidly and the downsampling coding is very efficient for bit rate reduction. With...