A correlation has been established between the absorbed fraction of training-set molecules after oral administration in humans and the Quantum Mechanical Polar Surface Area (QMPSA). This correlation holds for the QMPSA calculated with structures where carboxyl groups are deprotonated. The correlation of the absorbed fraction and the QMPSA calculated on the neutral gas phase optimized structures...

If a function f is of bounded variation on TN (N ≥ 1) and {φn} is a positive approximate identity, we prove that the area of the graph of f ∗φn converges from below to the relaxed area of the graph of f . Moreover we give asymptotic estimates for the area of the graph of the square partial sums of multiple Fourier series of functions with suitable discontinuities.

* Correspondence: [email protected] Department of Mathematics, China Three Gorges University, Yichang, 443002, China, Abstract Lutwak proposed the notion of Lp-geominimal surface area according to the Lpmixed volume. In this article, associated with the Lp-dual mixed volume, we introduce the Lp-dual geominimal surface area and prove some inequalities for this notion. 2000 Mathematics Subject Cla...

................................................................................................................................................... 4 FOREWORD .................................................................................................................................................. 8 CHAPTER 1 INTRODUCTION......................................................................

In a recent PSA paper (2001a), as well as some other papers (1995, 2000, 2001b) and a book chapter (1999, Chapter 7), Stathis Psillos raised a number of objections against structural realism. The aim of this paper is threefold: (1) to evaluate part of Psillos’ offence on the Russellian version of epistemic structural realism (ESR); (2) to elaborate more fully what Russellian ESR involves; and (...

In 2008, Wyoming was ranked 8th in barley production and 20th in hay production in the United States and these crops support Wyoming’s $800 million cattle industry. However, with a mean elevation of 2,040 meters, much of Wyoming has a limited crop growing season (as little as 60 days) and relies on late-summer and early-fall streamflow for agricultural water supply. Wyoming is host to over 80 g...

Common geometric models for proteins and other molecules are the space filling diagram, the solvent accessible surface, and the molecular surface. We descnbe software that compules metric properties of these models, including volume and surface area. It also measures voids or empty space enclosed by the protein, and it keeps track of surface area contributions of individual atoms. The software ...

We present a novel stereoscopic mapping system for use in post-nuclear accident operations. First we discuss a radiation shielded sensor array designed to tolerate extended cumulative dose using 4 shielding. Next, we outline procedures to ensure timely, accurate range estimation using trinocular stereo. Finally, we review the implementation of a system for the integration of range information i...