Background and Objective: The clinical outcomes and treatment options for acute myeloid leukemia (AML) patients are highly dependent upon molecular markers. In this study, Wilms tumor (WT1) (exons 7 and 9) mutations, SNP rs16754, and WT1 expression levels in 130 random AML patients were screened; FMs-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD), nucleophosmin (NPM1), and CCAAT/...

Life tables were calculated for 273 British children with cystic fibrosis for the period 1974-9. There was a marked improvement in survival rates in the meconium ileus group compared with the 1969-73 data, but there was little improvement in patients presenting later with other symptoms.

In this study, the effects of oxygen supplementation in different stocking densities of rainbow trout (Oncorhynchus mykiss) on the specific growth rates (SGR), feed conversion ratios (FCR) and survival rates were investigated in a commercial-scale culture system. High density cultures were maintained in a total of nine (12 m3) flow-through systems supplemented with O2. Initial stocking rates fo...

We consider a stochastic model for an evolving population. We show that in the presence of genotype extinctions the population dies out for a low mutation probability but may survive for a high mutation probability. This turns upside down the widely held belief that above a certain mutation threshold a population cannot survive. 1 A model with genotype extinctions There seems to be a consensus ...

In this study, the effects of oxygen supplementation in different stocking densities of rainbow trout (Oncorhynchus mykiss) on the specific growth rates (SGR), feed conversion ratios (FCR) and survival rates were investigated in a commercial-scale culture system. High density cultures were maintained in a total of nine (12 m3) flow-through systems supplemented with O2. Initial stocking rates fo...