This paper reviews the use of texture analysis in studying the performance of hydrophilic matrices of highly soluble drugs and different types of excipients (i.e. water-soluble, water-insoluble and swellable, and water insoluble and non-swellable). Tablets were prepared by direct compression, and their swelling and erosion in presence of these different excipients were assessed with the help of...

BACKGROUND AND THE PURPOSE OF THE STUDY Many drugs which have narrow therapeutic window and are absorbed mainly in stomach have been developed as gastroretentive delivery system. Rosiglitazone maleate, an anti-diabetic, is highly unstable at basic pH and is extensively absorbed from the stomach. Hence there is a need to develop a gastroretentive system. In this study a superporous hydrogel was ...

hydrogel nanocomposites based on alginate polysaccharide were prepared by graft copolymerization of acrylamide and itaconic acid in the presence of carbon nanotube, using methylene bisacrylamide and ammonium persulfate as crosslinker and initiator, respectively. the synthesized samples were characterized by infrared spectroscopy, thermogravimetric analysis and scanning electron microscopy. the ...

in order to determine outcome of pregnancy with lui in patients with unexplained recurrent miscarriage whose husbands have low hypo-osmotic swelling test scores, a prospective clinical intervention was performed at a university referral clinic of recurrent abortion. out of 56 patients whose husbands had abnormal hypo-osmotic swelling tests, 43 patients underwent lui, from which only 14 patients...

The purpose of our study is to develop a controlled Naproxen releasing system for anti-inflammatory, analgesic treatments. Interpenetrating polymer network (IPN) type hydrogels were obtained by using natural polymers alginate and gelatin. prepared combining Alginate Gelatin in the presence Glutaraldehyde as crosslinker Montmorillonite (MMT) clay was used nano-dimensioned layered dopant. charact...

To selectively remove mercury(II), 2-hydroxyethyl methacrylate (HM) and methacrylate/acrylamide (HM/ACR) hydrogels were synthesized using radiation. These used in swelling, diffusion, binding studies. Swelling parameters for HM/ACR−Hg2+ system are higher than those of HM−Hg2+ systems. Binding Hg2+ has been observed to be C-type HM L-type HM/ACR hydrogels. calculated Freundlich, Langmuir Henry m...