To investigate the immunomodulatory activity of flavonoid fractions of Terminalia catappa in Swiss albino mice. The flavonoid fraction of T.catappa was administrated intraperitonealy at a dose of ED50 to healthy albino mice. Assessment of immunomodulatory activity was carried out by assessment of neutrophil adhesion and phagocytic index. Intraperitonealy administered Tcff showed a significant i...

this study was designed to explore the protective effects of abrus precatorius l. (leguminosae) (ap) in hepg2 cells and n-nitrosodiethylamine (ndea) induced hepatocellular carcinoma in swiss albino rats. the effects of aqueous/ethanolic (50%) extract of ap on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in ndea (200 mg/kg and ccl4, 3 m...

Swiss Albino Mice........................................................... Inbred Mice................................................................ Hamsters................................................................. Squirrel Monkeys ......................................................... EFFECr ON RETENTION OF BACTERIA IN LUNGS................................. EFFECT ON LACTIC DEHY...

      This study was designed to explore the protective effects of Abrus precatorius L. (Leguminosae) (AP) in HepG2 cells and N-nitrosodiethylamine (NDEA) induced hepatocellular carcinoma in Swiss albino rats. The effects of aqueous/ethanolic (50%) extract of AP on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in NDEA ...

In the present study, the safety profile of Trichosanthes dioica root was evaluated by acute and sub-chronic toxicity study of the hydro alcoholic extract of T. dioica root (TDA) in Swiss albino mice. The oral median lethal dose (LD ) of TDA was found to be 2800 mg/kg body weight. For sub-chronic toxicity study 50 TDA was administered at the single daily dose of 10 mg/kg for 28 consecutive days...

The antinociceptive activity of the methanolic extract of the leaves of Feronia limonia Linn. (Family Rutaceae) was investigated using acetic acid-induced writhing model and tail flick test in swiss albino mice. The extract produced about 26.01% ( p< 0.01), 39.88% ( p< 0.01) and 57.07% (p< 0.01) writhing inhibition at the dose of 100, 200 and 400 mg/kg of body weight respectively, which was com...

The present study describes anticancer effect of gallic acid based indanone derivative (1). Indanone 1 exhibited in vivo anticancer activity against Erhlich ascites carcinoma in Swiss albino mice by inhibiting tumor growth by 54.3% at 50 mg/kg b.wt. It showed antitubulin effect by inhibiting tubulin polymerase enzyme. In cell cycle analysis, it inhibited G2/M phase and induced apoptosis. It sig...

Anxiety is a psychological and physiological state characterized by cognitive, somatic, emotional, and behavioural components. Benzodiazepines (BZDs) are the major class of compounds used in anxiety and they remain the most commonly prescribed treatment for anxiety. In the present study, we have attempted to evaluate the acute anxiolytic activity of aqueous extract of fruits of Terminalia chebu...