In October 1999, CDC, in collaboration with other federal partners, launched the National Plan to Eliminate Syphilis in the United States. In 1998, Congress initiated funding for the syphilis elimination effort. Syphilis elimination is defined as the absence of sustained transmission (i.e., no transmission after 90 days of the report of an imported index case). The national goal for syphilis el...

Syphilis in pregnancy is a worrisome topic due to its fetal consequences. The diagnosis and management of such case might be intriguing when overlapped with Behçet’s disease, an inflammatory disease involving multiple organ systems. This presents 35-year-old pregnant female, known hypothyroidism, presenting at 33 weeks the emergency department Bahrain Defense Force (BDF) hospital vaginal leakin...

Investigating the predictors for lumbar puncture to diagnose the asymptomatic neurosyphilis among HIV and syphilis co-infected patients in Shanghai, China. Respectively, screening the medical records from August 1, 2009 to June 30, 2015. Those HIV-infected patients with concurrent syphilis who had received lumbar puncture were selected and their clinical and demographic data were recorded. Part...

Syphilis serology is a basic screening test for the workers who want to go abroad. Many countries reject migrant workers who have reactive syphilis serology. Biological false reactives warrant repeated syphilis serology. We prospectively studied 30 patients (25 males and 5 females) who had biological false reactive VDRL tests (VDRL reactive, confirmatory TPHA negative). Affirmative tests for sy...

PROBLEM Early detection of syphilis-infected people followed by effective treatment is essential for syphilis prevention and control. APPROACH Starting in 2010 the local health authority in Yunnan province, China, developed a network of 670 service sites for syphilis testing, diagnosis and treatment or for testing-only with referral for further diagnosis and treatment. Point-of-care tests for...

Objective To investigate the adverse pregnancy outcomes and associated risk factors among pregnant women with syphilis. Design Pregnant syphilis in registry for prevention of mother-to-child transmission AIDS, hepatitis B Hunan Province, China, from January 1, 2013 to December 31, 2018 were included study. Results Among 14,219 syphilis, 11,346 had definite singleton pregnancy. The related inclu...

BACKGROUND Serology is the mainstay for syphilis diagnosis and treatment monitoring. We investigated serological response to treatment of syphilis according to disease stage and HIV status. METHODS A retrospective cohort study of 264 patients with syphilis was conducted, including 90 primary, 133 secondary, 33 latent, and 8 tertiary syphilis cases. Response to treatment as measured by the Ven...

BACKGROUND HIV and congenital syphilis are major public health burdens contributing to substantial perinatal morbidity and mortality globally. Although studies have reported on the costs and cost-effectiveness of rapid diagnostic tests (RDTs) for syphilis screening within antenatal care in a number of resource-constrained settings, empirical evidence on country-specific cost and estimates of si...

Background. The prevalence of syphilis among HIV-infected people is a public health concern, but there is limited literature to describe the true burden of syphilis in resource-limited settings. We conducted this survey in 2013 to estimate the prevalence of syphilis. Methods. A cross-sectional survey. Participants were tested for syphilis and HIV. Factors associated with syphilis infection were...

Syphilitic Aortitis in Secondary Syphilis Syphilis is a mainly sexually transmitted infection that may show a variety of symptoms at various stages. Syphilitic aortitis is a knowncomplicationof tertiary syphilis and can cause aneurysmof the aorta.1 In the era of antibiotics, cardiovascular syphilis has become very rare.2 Nevertheless it can cause life-threatening or even fatal symptoms and shou...