نتایج جستجو برای: systemic mastocytosis
تعداد نتایج: 175955 فیلتر نتایج به سال:
Patients with advanced variants of Systemic Mastocytosis may develop destructive bone lesions when massive mast cell (MC) infiltrates are present. Finding of large osteolyses in indolent systemic mastocytosis, typically characterized by low MC burden, should prompt investigations for an alternative explanation.
NR: Not reported, FCR: fludarabine, cyclophosphamide, rituximab; MUD AHSCT: matched unrelated donor allogeneic hematopoietic stem cell transplantation, CR: complete remission, CLL: chronic lymphocytic leukemia, SM: systemic mastocytosis. Systemic Mastocytosis with Associated Chronic Lymphocytic Leukemia: A Matter of Diseases or Prognostic Factors? Kronik Lenfositik Lösemi ile Birlikte Seyreden ...
Cutaneous mastocytosis is a rare infiltrative disorder of the skin. Though often asymptomatic, systemic features may be associated with any clinical pattern of the disorder at any age group. We present our experience with six cases of cutaneous mastocytosis, including three with diffuse cutaneous mastocytosis, a rare entity.
A patient with a history of non-diagnostic bone marrow biopsies presented with a red to brown maculopapular rash on the back. Biopsies confirmed multiple xanthogranulomas as well as a mastocytosis. A consequently performed bone marrow biopsy verified a systemic mastocytosis and a chronic myelomonocytic leukemia (CMML) type I. HERE, WE DESCRIBE FOR THE FIRST TIME IN THE LITERATURE A PATIENT WITH...
Clonal expansion of mast cells carrying the D816V c-kit mutation results in mastocytosis. Recent studies identified the presence of clonal mast cells carrying this mutation in patients with anaphylaxis without classic diagnostic findings of systemic mastocytosis.
Cytogenetic analysis of bone marrow cells and in vitro growth for bone marrow granulocytic-macrophage stem cells have been performed in 13 patients with mastocytosis, six with systemic mastocytosis, and seven with urticaria pigmentosa. Clones with chromosome abnormalities were found in five patients. The number of clusters and/or colonies after seven days in culture was increased in seven patie...
Mastocytosis is a heterogeneous group of rare diseases related to the clonal, neoplastic proliferation morphologically and immunophenotypically abnormal mast cells, that accumulate in one or more organ systems. Their pathophysiology dominated by activating mutations C-Kit (Stem Cell Factor receptor). Several pathological forms have been described ranging from isolated cutaneous mastocytosis aff...
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