Despite being empirically designed based on a simple understanding of TCR signaling, T cells engineered with chimeric antigen receptors (CARs) have been remarkably successful in treating patients with advanced refractory B cell malignancies. However, many challenges remain in improving the safety and efficacy of this therapy and extending it toward the treatment of epithelial cancers. Other asp...

This paper presents a new approach for intuitively modeling a 3D garment around a 3D human model by 2D sketches input. Our approach is feature based – every human model has pre-defined features, and the constructed garments are related to the features on human models. Firstly, a feature template for creating a customized 3D garment is defined according to the features on a human model; secondly...

T-spline surfaces are a powerful tool in geometric modelling. A T-spline surface is an approximation of a T-grid data structure. T-grids support adaption operations like local refinement or merging of existing NURBS grids. Digital terrain models based on T-spline surfaces benefit from non-regular control grids. We show some exemplary application cases for T-spline based terrain modelling.