BACKGROUND: The oxidative modification hypothesis of atherosclerosis predicts that low density lipoprotein-cholesterol (LDL-C) oxidation is an early event in atherosclerosis and that oxidized LDL-C contributes to atherogenesis OBJECTIVE: To determine a link, if any, between the plasma lipid peroxidation and total antioxidant status (TAS) among dyslipidemic and hypertensive Nigerian patients wit...

background: hypercholesterolemia is one of the risk factors of cardiovascular diseases. it affects general health and increases cardiovascular mortality rate. diet with high cholesterol increases ldl that, inturn, decrease ldl receptors activity in liver. oxidation of vessel wall lipoproteins increases development of atherosclerosis. several evidences suggest that antioxidants consumption decre...

OBJECTIVE To assess the relation between serum lipids and memory in a healthy middle age cohort of women. METHODS For 326 women in the Melbourne Women's Midlife Health Project aged 52-63 years, serum lipids were measured annually, and memory was assessed during the eighth annual visit. RESULTS There was a small but significant association between current low density lipoprotein cholesterol ...

OBJECTIVE We sought to determine if arterial LDL metabolism contributes to the decreased atherosclerosis seen with soy and if isolated isoflavones would have similar effects. METHODS AND RESULTS Ovariectomized monkeys were fed an atherogenic diet for 20 weeks with a protein source of (1) casein/lactalbumin (CAS, n=20), (2) soy protein isolate (SOY, n=20), or (3) casein/lactalbumin with isolat...

Technetium-labeled low density lipoproteins (Tc-LDL) appear to be useful for describing LDL biodistribution in normal and dyslipidemic subjects. We injected 99mTc-LDL into subjects with large tendon xanthomas secondary to homozygous familial hypercholesterolemia or sitosterolemia. Rapid (4 hours) accumulation of Tc-99m activity in xanthomas was observed, and this accumulation increased over a 2...

OBJECTIVE To assess the relationship of serum lipid concentrations with glucose control in youth with diabetes mellitus. DESIGN Cross-sectional analyses of data from the SEARCH for Diabetes in Youth study. SETTING Multicenter study of youth with diabetes onset at younger than 20 years. PATIENTS/ PARTICIPANTS: Nineteen hundred seventy-three SEARCH participants aged 10 years or older with hem...

Dyslipidemia is one of the major risk factors of coronary artery disease. Present study was aimed to find out the lipid profile of non-diabetic adult Nepalese population (n = 454; M: 180 and F: 274; Mean age: 42.8+/-15.5 years). The mean +/- SD (mg/dl) level of total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) was 184+/-50.7, 147.4+/-79....

conclusions decreases of tc, ldl and tg may be related to tomato antioxidant effect. this course in human required more investigations. results results showed that in chol group, all lipids increased significantly (p < 0.05) except hdl compared to the control group. tomato and tomato paste supplementation decreased tc, ldl and tg concentration significantly (p < 0.05) compared to chol group. to...